Rohit Majumdar1, Nancy F Crum-Cianflone2. 1. Infectious Diseases Department, Scripps Mercy Hospital, 4077 Fifth Ave, San Diego, CA, 92103, USA. rohitmajumdar5@gmail.com. 2. Infectious Diseases Department, Scripps Mercy Hospital, 4077 Fifth Ave, San Diego, CA, 92103, USA. nancy32red@yahoo.com.
Abstract
BACKGROUND: Necrotizing fasciitis is a severe, life-threatening infection. Serratia marcescens, a Gram-negative bacterium, is an extremely rare cause of necrotizing fasciitis. METHODS: A case of S. marcescens necrotizing fasciitis is described, and a comprehensive review of the literature (1966-2015) of monomicrobial cases due to this organism performed. RESULTS: We report the first case of S. marcescens necrotizing fasciitis in the setting of calciphylaxis associated with end-stage renal disease. A comprehensive review of the literature of S. marcescens necrotizing fasciitis is provided to enhance the awareness of this increasingly recognized infection, and to provide a concise summary of risk factors, treatment, and outcome. CONCLUSIONS: Our case and review highlight the potential risk factors for S. marcescens necrotizing fasciitis, including underlying renal disease and open wounds, and demonstrate the emergence of this organism as a cause of severe, life-threatening soft tissue infections.
BACKGROUND:Necrotizing fasciitis is a severe, life-threatening infection. Serratia marcescens, a Gram-negative bacterium, is an extremely rare cause of necrotizing fasciitis. METHODS: A case of S. marcescensnecrotizing fasciitis is described, and a comprehensive review of the literature (1966-2015) of monomicrobial cases due to this organism performed. RESULTS: We report the first case of S. marcescensnecrotizing fasciitis in the setting of calciphylaxis associated with end-stage renal disease. A comprehensive review of the literature of S. marcescensnecrotizing fasciitis is provided to enhance the awareness of this increasingly recognized infection, and to provide a concise summary of risk factors, treatment, and outcome. CONCLUSIONS: Our case and review highlight the potential risk factors for S. marcescensnecrotizing fasciitis, including underlying renal disease and open wounds, and demonstrate the emergence of this organism as a cause of severe, life-threatening soft tissue infections.
Authors: Melissa M Statham; Amit Vohra; Deepak K Mehta; Troy Baker; Robert Sarlay; Michael J Rutter Journal: Int J Pediatr Otorhinolaryngol Date: 2008-12-10 Impact factor: 1.675