| Literature DB >> 2649750 |
J C Eisenach1, D J Plevak, R A Van Dyke, P A Southorn, D R Danielson, R A Krom, D M Nagorney, S R Rettke.
Abstract
In a prospective study of 10 patients who underwent liver transplantation and 10 patients who underwent cholecystectomy, we analyzed the postoperative analgesic requirements and the resultant plasma morphine concentrations. Analgesia was more intense, with less medication, and the plasma morphine concentration was significantly lower in the liver transplant group than in the cholecystectomy group. This finding is most likely attributable to endogenous factors rather than to altered morphine pharmacokinetics.Entities:
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Year: 1989 PMID： 2649750 DOI： 10.1016/s0025-6196(12)65257-4
Source DB: PubMed Journal: Mayo Clin Proc ISSN： 0025-6196 Impact factor: 7.616