| Literature DB >> 2649747 |
D Smith1, S Sanjar, C Herd, J Morley.
Abstract
Platelets labeled with 111Indium have been injected intravenously into anesthetised guinea pigs, and intrathoracic content of 111Indium-labeled platelets has been monitored continuously using a microcomputer-based system (AIMSplus). Dose-effect relationships have been described for ADP, collagen, and PAF, and effects of drugs upon selected responses illustrate the potential of this test system for routine in vivo screening of agents that may inhibit aggregation of platelets.Entities:
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Year: 1989 PMID： 2649747 DOI： 10.1016/0160-5402(89)90021-1
Source DB: PubMed Journal: J Pharmacol Methods ISSN： 0160-5402