Literature DB >> 26496212

Multidisciplinary approach of lumbo-sacral chordoma: From oncological treatment to reconstructive surgery.

Fabio Garofalo1, Pietro G di Summa2, Dimitrios Christoforidis1,3, Marc Pracht4, Pietro Laudato5, Stéphane Cherix5, Hanan Bouchaab6, Wassim Raffoul2, Nicolas Demartines1, Maurice Matter1.   

Abstract

Lumbo-sacral chordoma is a rare, slow-growing tumor, arising from embryonic nothocordal remnants. Wide en bloc excision with clear margins remains mandatory to achieve satisfactory recurrence rates and disease-free survival. No chemotherapy has been demonstrated to be effective and radiotherapy is only marginally effective. Tyrosine kinase receptor inhibitors have showed encouraging results in locally advanced and metastatic chordoma. Reconstructive surgery may become very complex. Multidisciplinary approach in tertiary hospitals is always necessary.
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  chordoma; sacrum; spine

Mesh：

Year:  2015        PMID： 26496212     DOI： 10.1002/jso.24026

Source DB:  PubMed          Journal:  J Surg Oncol        ISSN： 0022-4790            Impact factor:   3.454


  7 in total

1.  Low dose radiotherapy is associated with local complications but not disease control in sacral chordoma.

Authors:  Matthew T Houdek; Peter S Rose; Mario Hevesi; Joseph H Schwab; Anthony M Griffin; John H Healey; Ivy A Petersen; Thomas F DeLaney; Peter W Chung; Michael J Yaszemski; Jay S Wunder; Francis J Hornicek; Patrick J Boland; Franklin H Sim; Peter C Ferguson
Journal:  J Surg Oncol       Date:  2019-02-07       Impact factor: 3.454

2.  Sacral Defect Reconstruction Using Double Pedicled Gracilis Muscle Flap combined with Gluteal Fasciocutaneous Rotation Flap.

Authors:  Julie C Triolo; Nicolas C Buchs; Enrico Tessitore; Didier Hannouche; Dennis E Dominguez; Daniel F Kalbermatten; Carlo M Oranges
Journal:  Plast Reconstr Surg Glob Open       Date:  2022-05-16

3.  A modern multidisciplinary approach to a large cervicothoracic chordoma using staged en bloc resection with intraoperative image-guided navigation and 3D-printed modeling: illustrative case.

Authors:  Nathan J Pertsch; Owen P Leary; Joaquin Q Camara-Quintana; David D Liu; Tianyi Niu; Albert S Woo; Thomas T Ng; Adetokunbo A Oyelese; Jared S Fridley; Ziya L Gokaslan
Journal:  J Neurosurg Case Lessons       Date:  2021-02-08

4.  Proteomics and phosphoproteomics of chordoma biopsies reveal alterations in multiple pathways and aberrant kinases activities.

Authors:  Jing Hang; Hanqiang Ouyang; Feng Wei; Qihang Zhong; Wanqiong Yuan; Liang Jiang; Zhongjun Liu
Journal:  Front Oncol       Date:  2022-09-30       Impact factor: 5.738

5.  A histological examination of spinal reconstruction using a frozen bone autograft.

Authors:  Kazuya Shinmura; Hideki Murakami; Satoru Demura; Satoshi Kato; Katsuhito Yoshioka; Hiroyuki Hayashi; Kei Inoue; Takashi Ota; Noriaki Yokogawa; Takayoshi Ishii; Takashi Igarashi; Hiroyuki Tsuchiya
Journal:  PLoS One       Date:  2018-01-25       Impact factor: 3.240

6.  Surgical nuances of partial sacrectomy for chordoma.

Authors:  Sergei Terterov; Daniel Diaz-Aguilar; Rudi Scharnweber; Alex Tucker; Tianyi Niu; Jos'lyn Woodard; Harsimran Brara; Melissa Poh; Catherine Merna; Stephanie Wang; Shayan Rahman
Journal:  Surg Neurol Int       Date:  2017-11-20

7.  Revision surgery for instrumentation failure after total en bloc spondylectomy: a retrospective case series.

Authors:  Kazuya Shinmura; Satoshi Kato; Satoru Demura; Noriaki Yokogawa; Noritaka Yonezawa; Takaki Shimizu; Norihiro Oku; Ryo Kitagawa; Makoto Handa; Ryohei Annen; Hideki Murakami; Hiroyuki Tsuchiya
Journal:  BMC Musculoskelet Disord       Date:  2020-09-02       Impact factor: 2.362
  7 in total

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