Literature DB >> 26492982

Withanolides and Sucrose Esters from Physalis neomexicana.

Cong-Mei Cao, Xiaoqing Wu, Kelly Kindscher1, Liang Xu, Barbara N Timmermann.   

Abstract

Four withanolides (1-4) and two sucrose esters (5, 6) were isolated from the aerial parts of Physalis neomexicana. The structures of 1-6 were elucidated through a variety of spectroscopic techniques. Cytotoxicity studies of the isolates revealed that 2 inhibited human breast cancer cell lines (MDA-MB-231 and MCF-7) with IC50 values of 1.7 and 6.3 μM, respectively.

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Year:  2015        PMID: 26492982     DOI: 10.1021/acs.jnatprod.5b00698

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  5 in total

1.  Stereo- and region-specific biotransformation of physapubescin by four fungal strains.

Authors:  Chongyue Qiu; Ting Yuan; Dejuan Sun; Suyu Gao; Lixia Chen
Journal:  J Nat Med       Date:  2017-01-10       Impact factor: 2.343

2.  New withanolides from Physalis minima and their cytotoxicity against A375 human melanoma cells.

Authors:  Meng Zhang; Bingyang Zhang; Chenxi Guang; Benke Jiang; Xinya He; Shijie Cao; Liqin Ding; Ning Kang; Lixia Chen; Feng Qiu
Journal:  RSC Adv       Date:  2020-06-16       Impact factor: 4.036

Review 3.  Fruity, sticky, stinky, spicy, bitter, addictive, and deadly: evolutionary signatures of metabolic complexity in the Solanaceae.

Authors:  Paul D Fiesel; Hannah M Parks; Robert L Last; Cornelius S Barry
Journal:  Nat Prod Rep       Date:  2022-07-20       Impact factor: 15.111

Review 4.  Recent Advances in the Chemistry and Therapeutic Evaluation of Naturally Occurring and Synthetic Withanolides.

Authors:  Amandeep Singh; Asif Raza; Shantu Amin; Chendil Damodaran; Arun K Sharma
Journal:  Molecules       Date:  2022-01-28       Impact factor: 4.411

Review 5.  Natural Withanolides in the Treatment of Chronic Diseases.

Authors:  Peter T White; Chitra Subramanian; Hashim F Motiwala; Mark S Cohen
Journal:  Adv Exp Med Biol       Date:  2016       Impact factor: 2.622

  5 in total

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