Literature DB >> 2649223

A case of fatal pemphigus vulgaris in association with beta interferon and interleukin-2 therapy.

W L Ramseur1, F Richards, D B Duggan.   

Abstract

Beta interferon (beta-IFN) and interleukin-2 (IL-2) have been utilized in experimental cancer therapy because of their effects on the immune system. We report here a patient treated with IL-2 and beta-IFN who rapidly developed an immune-mediated, bullous exfoliative dermatitis and who ultimately died. Various etiologic mechanisms are proposed.

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Year:  1989        PMID： 2649223     DOI： 10.1002/1097-0142(19890515)63:10<2005::aid-cncr2820631023>3.0.co;2-p

Source DB:  PubMed          Journal:  Cancer        ISSN： 0008-543X            Impact factor:   6.860


  2 in total

Review 1.  Clinical toxicity of interleukin-2.

Authors:  T Vial; J Descotes
Journal:  Drug Saf       Date:  1992 Nov-Dec       Impact factor: 5.606

2.  Lobular panniculitis after subcutaneous administration of interleukin-2 (IL-2), and its exacerbation during intravenous therapy with IL-2.

Authors:  J W Baars; J L Coenen; J Wagstaff; P van der Valk; H M Pinedo
Journal:  Br J Cancer       Date:  1992-10       Impact factor: 7.640
  2 in total

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