Literature DB >> 2649148

Effects of fusidic acid on staphylococcal keratitis.

K F Tabbara1, S Antonios, H Alvarez.   

Abstract

We treated 20 consecutive patients suffering from staphylococcal keratitis with topical fusidic acid 1% suspension in a carbomer gel. Fifteen (79%) of the isolated Staphylococcus epidermidis strains were resistant to methicillin, but all were sensitive to fusidic acid by in-vitro testing. The keratitis showed evidence of healing in 17 (85%) of the 20 patients. The healing times ranged between 5 and 21 days (mean 10.5 days). In this open clinical trial fusidic acid proved to be a safe and effective antibiotic for the treatment of staphylococcal keratitis.

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Year:  1989        PMID: 2649148      PMCID: PMC1041671          DOI: 10.1136/bjo.73.2.136

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  10 in total

1.  Further observations on the diagnosis cause, and treatment of endophthalmitis.

Authors:  R K Forster; I G Zachary; A J Cottingham; E W Norton
Journal:  Am J Ophthalmol       Date:  1976-01       Impact factor: 5.258

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Authors:  R B CROSBIE
Journal:  Br Med J       Date:  1963-03-23

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Authors:  R A Hyndiuk; G N Chin
Journal:  Int Ophthalmol Clin       Date:  1973

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Authors:  I J Copperman
Journal:  Br J Clin Pract       Date:  1972-02

5.  Effect of preoperative fusidic acid on the normal eyelid and conjunctival bacterial flora.

Authors:  P B Taylor; K F Tabbara; E M Burd
Journal:  Br J Ophthalmol       Date:  1988-03       Impact factor: 4.638

6.  Changing resistance to antimicrobial drugs, and resistance typing in clinically significant strains of Staphylococcus epidermidis.

Authors:  J F Richardson; R R Marples
Journal:  J Med Microbiol       Date:  1982-11       Impact factor: 2.472

7.  Steroid antibiotics.

Authors:  G T Stewart
Journal:  Pharmakotherapia       Date:  1964

8.  Corneal and intraocular penetration of topical and subconjunctival fusidic acid.

Authors:  P B Taylor; E M Burd; K F Tabbara
Journal:  Br J Ophthalmol       Date:  1987-08       Impact factor: 4.638

9.  Topical vancomycin formulation for methicillin-resistant Staphylococcus epidermidis blepharoconjunctivitis.

Authors:  A B Fleischer; D L Hoover; J A Khan; J T Parisi; R P Burns
Journal:  Am J Ophthalmol       Date:  1986-03-15       Impact factor: 5.258

10.  Methicillin-resistant Staphylococcus epidermidis blepharitis.

Authors:  J A Khan; D Hoover; C H Ide
Journal:  Am J Ophthalmol       Date:  1984-11       Impact factor: 5.258

  10 in total
  1 in total

1.  [Methicillin-resistant Staphylococcus epidermidis infectious keratitis: Clinical and microbiological profile].

Authors:  L Vidal Oliver; P Bayo Calduch; L Forqué Rodríguez; D Navarro Ortega; A M Duch Samper; J Colomina Rodríguez
Journal:  Rev Esp Quimioter       Date:  2022-01-24       Impact factor: 1.553

  1 in total

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