Literature DB >> 2649098

Half-life of proteasomes (multiprotease complexes) in rat liver.

K Tanaka1, A Ichihara.   

Abstract

Proteasomes (large multicatalytic proteinase complexes) are abundant in rat liver, constituting approximately 1.0% of the total soluble proteins. In the present study, the apparent half-life of the proteasomes was determined to be 12-15 days from the decay curve of isotopically labeled enzymes in vivo, suggesting their slow turnover. This finding together with the ubiquitous distribution of proteasomes in eukaryotic cells (Tanaka et al., 1988 J. Biol. Chem. 263, 16209-16217) indicates that proteasomes belong to a family of proteins with house-keeping function.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2649098     DOI： 10.1016/0006-291x(89)92253-5

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  27 in total

1.  Disruption of prosomes by some bivalent metal ions results in the loss of their multicatalytic proteinase activity and cancels the nuclease resistance of prosomal RNA.

Authors:  H G Nothwang; O Coux; F Bey; K Scherrer
Journal:  Biochem J       Date:  1992-11-01       Impact factor: 3.857

2.  PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis.

Authors:  Katsuhiro Sasaki; Jun Hamazaki; Masato Koike; Yuko Hirano; Masaaki Komatsu; Yasuo Uchiyama; Keiji Tanaka; Shigeo Murata
Journal:  Mol Cell Biol       Date:  2010-05-24       Impact factor: 4.272

3.  Characterization of the Interaction between the Matrix Protein of Vesicular Stomatitis Virus and the Immunoproteasome Subunit LMP2.

Authors:  Frauke Beilstein; Linda Obiang; Hélène Raux; Yves Gaudin
Journal:  J Virol       Date:  2015-08-26       Impact factor: 5.103

4.  Proteasomes are regulated by interferon gamma: implications for antigen processing.

Authors:  Y Yang; J B Waters; K Früh; P A Peterson
Journal:  Proc Natl Acad Sci U S A       Date:  1992-06-01       Impact factor: 11.205

5.  Intermediates in the formation of mouse 20S proteasomes: implications for the assembly of precursor beta subunits.

Authors:  D Nandi; E Woodward; D B Ginsburg; J J Monaco
Journal:  EMBO J       Date:  1997-09-01       Impact factor: 11.598

6.  Dynamics of proteasome distribution in living cells.

Authors:  E A Reits; A M Benham; B Plougastel; J Neefjes; J Trowsdale
Journal:  EMBO J       Date:  1997-10-15       Impact factor: 11.598

7.  Two alternative mechanisms regulate the onset of chaperone-mediated assembly of the proteasomal ATPases.

Authors:  Asrafun Nahar; Xinyi Fu; George Polovin; James D Orth; Soyeon Park
Journal:  J Biol Chem       Date:  2019-02-27       Impact factor: 5.157

8.  p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome.

Authors:  Victoria Cohen-Kaplan; Ido Livneh; Noa Avni; Bertrand Fabre; Tamar Ziv; Yong Tae Kwon; Aaron Ciechanover
Journal:  Proc Natl Acad Sci U S A       Date:  2016-10-17       Impact factor: 11.205

9.  HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress.

Authors:  Tilman Grune; Betül Catalgol; Anke Licht; Gennady Ermak; Andrew M Pickering; Jenny K Ngo; Kelvin J A Davies
Journal:  Free Radic Biol Med       Date:  2011-06-24       Impact factor: 7.376

10.  Phylogenic relationships of the amino acid sequences of prosome (proteasome, MCP) subunits.

Authors:  O Coux; H G Nothwang; I Silva Pereira; F Recillas Targa; F Bey; K Scherrer
Journal:  Mol Gen Genet       Date:  1994-12-15
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.