Literature DB >> 2649091

Differentiation of rapid and slower-acting effects of insulin on mitochondrial processes in brown adipose tissue from streptozotocin-diabetic rats.

A Gualberto1, E D Saggerson.   

Abstract

Insulin treatment of streptozotocin-diabetic rats restores the depressed palmitoyl-group oxidation observed in brown-adipose-tissue mitochondria from diabetic rats. A relatively rapid effect of insulin (5 h) to increase carnitine-dependent oxidation of palmitoyl-CoA and to increase overt carnitine palmitoyltransferase activity is differentiated from a slower effect of the hormone (1 day) to increase palmitoylcarnitine oxidation.

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Year:  1989        PMID: 2649091      PMCID: PMC1138357          DOI: 10.1042/bj2580309

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  10 in total

1.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

2.  Modulation of beta-oxidation and proton conductance pathway of brown adipose tissue in hypo- and hyperinsulinemic states.

Authors:  J Seydoux; E R Trimble; F Bouillaud; F Assimacopoulos-Jeannet; S Bas; D Ricquier; J P Giacobino; L Girardier
Journal:  FEBS Lett       Date:  1984-01-23       Impact factor: 4.124

3.  Role of insulin in thermogenic responses to refeeding in 3-day-fasted rats.

Authors:  N J Rothwell; M E Saville; M J Stock
Journal:  Am J Physiol       Date:  1983-08

4.  Carnitine acyltransferase activities in rat liver and heart measured with palmitoyl-CoA and octanoyl-CoA. Latency, effects of K+, bivalent metal ions and malonyl-CoA.

Authors:  E D Saggerson
Journal:  Biochem J       Date:  1982-02-15       Impact factor: 3.857

5.  Some aspects of fatty acid oxidation in isolated fat-cell mitochondria from rat.

Authors:  R D Harper; E D Saggerson
Journal:  Biochem J       Date:  1975-12       Impact factor: 3.857

6.  Factors influencing the altered thermogenic response of rat brown adipose tissue in streptozotocin-diabetes.

Authors:  Z Jamal; E D Saggerson
Journal:  Biochem J       Date:  1988-01-15       Impact factor: 3.857

7.  Changes in brown-adipose-tissue mitochondrial processes in streptozotocin-diabetes.

Authors:  Z Jamal; E D Saggerson
Journal:  Biochem J       Date:  1988-05-15       Impact factor: 3.857

8.  Brown adipose tissue metabolism in streptozotocin-diabetic rats.

Authors:  J Seydoux; A Chinet; G Schneider-Picard; S Bas; E Imesch; F Assimacopoulos-Jeannet; J P Giacobino; L Girardier
Journal:  Endocrinology       Date:  1983-08       Impact factor: 4.736

9.  Glucagon treatment of rats inhibits the accumulation of lysophospholipids by liver mitochondria during preparation and subsequent incubation.

Authors:  A E Armston; A P Halestrap
Journal:  Biosci Rep       Date:  1984-11       Impact factor: 3.840

10.  A role for insulin in the diet-induced thermogenesis of cafeteria-fed rats.

Authors:  N J Rothwell; M J Stock
Journal:  Metabolism       Date:  1981-07       Impact factor: 8.694

  10 in total
  2 in total

1.  Activities of enzymes of glycerolipid synthesis in brown adipose tissue after treatment of rats with the adrenergic agonists BRL 26830A and phenylephrine, after exposure to cold and in streptozotocin-diabetes.

Authors:  J R Mitchell; E D Saggerson
Journal:  Biochem J       Date:  1991-08-01       Impact factor: 3.857

2.  Effects of hypothyroidism and hyperthyroidism on GDP binding to brown-adipocyte mitochondria from rats.

Authors:  J A Woodward; E D Saggerson
Journal:  Biochem J       Date:  1989-10-15       Impact factor: 3.857

  2 in total

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