Taku Inohara1, Kentaro Hayashida1, Yusuke Watanabe2, Masanori Yamamoto3, Kensuke Takagi4, Fumiaki Yashima1, Takahide Arai1,5, Hideyuki Shimizu6, Bernard Chevalier5, Thierry Lefèvre5, Keiichi Fukuda1, Marie-Claude Morice5. 1. Department of Cardiology, Keio University School of Medicine, Tokyo, Japan. 2. Division of Cardiology, Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan. 3. Division of Cardiovascular Medicine, Toyohashi Heart Center, Toyohashi, Japan. 4. Interventional Cardiology Unit, New Tokyo Hospital, Chiba, Japan. 5. Department of Interventional Cardiology, Institut Cardiovasculaire Paris Sud, Massy, France. 6. Department of Cardiovascular Surgery, Keio University School of Medicine, Tokyo, Japan.
Abstract
BACKGROUNDS: To facilitate the learning process of transcatheter aortic valve implantation (TAVI) in Japan, unique supporting systems (e.g., on-site proctor and web-based screening systems) have been developed. Nevertheless, little is known about real-world clinical outcomes after TAVI in Japan compared with their European counterparts. METHODS: From the optimized catheter valvular intervention (OCEAN-TAVI, Japan) and the Institut Cardiovasculaire Paris Sud (Massy, France) registries, we evaluated a total of 134 and 178 patients, respectively, who underwent transfemoral TAVI during the same time period. RESULTS: Among the French cohort, about half of the patients (N = 81, 45.5%) were treated with the Edwards SAPIEN XT. Body surface area was significantly smaller in the Japanese cohort, although operative risks for both cohorts were almost the same. A greater percentage of patients in the Japanese cohort were implanted with 23 mm valves compared with the French cohort (73.1% vs. 23.0%, P < 0.001), reflecting the smaller annulus diameter (21.8 ± 1.6 vs. 23.8 ± 2.4 mm, P < 0.001). All-cause 30-day mortality (0% vs. 0.6%, P = 1.000) and 30-day combined safety endpoint based on the Valve Academic Research Consortium 2 (VARC2) criteria (9.7% vs. 11.2%, P = 0.713) were similar when limiting the analysis to patients treated with the Edwards SAPIEN XT. CONCLUSIONS: Despite the unfavorable aortic anatomy of the Japanese patients, their clinical outcomes after transfemoral TAVI were excellent with the same degree of safety as in an experienced European institute. This minimized learning process achieved the use of unique support systems.
BACKGROUNDS: To facilitate the learning process of transcatheter aortic valve implantation (TAVI) in Japan, unique supporting systems (e.g., on-site proctor and web-based screening systems) have been developed. Nevertheless, little is known about real-world clinical outcomes after TAVI in Japan compared with their European counterparts. METHODS: From the optimized catheter valvular intervention (OCEAN-TAVI, Japan) and the Institut Cardiovasculaire Paris Sud (Massy, France) registries, we evaluated a total of 134 and 178 patients, respectively, who underwent transfemoral TAVI during the same time period. RESULTS: Among the French cohort, about half of the patients (N = 81, 45.5%) were treated with the Edwards SAPIEN XT. Body surface area was significantly smaller in the Japanese cohort, although operative risks for both cohorts were almost the same. A greater percentage of patients in the Japanese cohort were implanted with 23 mm valves compared with the French cohort (73.1% vs. 23.0%, P < 0.001), reflecting the smaller annulus diameter (21.8 ± 1.6 vs. 23.8 ± 2.4 mm, P < 0.001). All-cause 30-day mortality (0% vs. 0.6%, P = 1.000) and 30-day combined safety endpoint based on the Valve Academic Research Consortium 2 (VARC2) criteria (9.7% vs. 11.2%, P = 0.713) were similar when limiting the analysis to patients treated with the Edwards SAPIEN XT. CONCLUSIONS: Despite the unfavorable aortic anatomy of the Japanese patients, their clinical outcomes after transfemoral TAVI were excellent with the same degree of safety as in an experienced European institute. This minimized learning process achieved the use of unique support systems.
Authors: Gudrun Lamm; Matthias Hammerer; Uta C Hoppe; Martin Andreas; Rudolf Berger; Ronald K Binder; Nikolaos Bonaros; Georg Delle-Karth; Matthias Frick; Michael Grund; Bernhard Metzler; Thomas Neunteufl; Philipp Pichler; Albrecht Schmidt; Wilfried Wisser; Andreas Zierer; Rainald Seitelberger; Michael Grimm; Alexander Geppert Journal: Wien Klin Wochenschr Date: 2021-03-23 Impact factor: 1.704
Authors: Tsuyoshi Kaneko; Sreekanth Vemulapalli; Shun Kohsaka; Kazuo Shimamura; Amanda Stebbins; Hiraku Kumamaru; Adam J Nelson; Andrzej Kosinski; Koichi Maeda; Joseph E Bavaria; Shigeru Saito; Michael J Reardon; Toru Kuratani; Jeffrey J Popma; Taku Inohara; Vinod H Thourani; John D Carroll; Hideyuki Shimizu; Morimasa Takayama; Martin B Leon; Michael J Mack; Yoshiki Sawa Journal: J Am Heart Assoc Date: 2022-03-04 Impact factor: 6.106