Literature DB >> 2648881

Stage specific actions of antimalarial drugs on Plasmodium falciparum in culture.

T G Geary1, A A Divo, J B Jensen.   

Abstract

Chemicals with antimalarial effects show different patterns against ring stages, trophozoites, and schizonts of Plasmodium falciparum in culture. Amodiaquine, mefloquine, quinine, quinacrine, primaquine, qinghaosu, halofantrine, rifampin, antimycin A1, cycloheximide, and actinomycin D were preferentially toxic to the mature stages. Ammonium chloride killed ring stages faster than mature forms, while tetracycline, clindamycin, and halofuginone acted with equal speed on all 3 stages.

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Year:  1989        PMID： 2648881     DOI： 10.4269/ajtmh.1989.40.240

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  31 in total

Review 1.  Pharmacology and parasitology: integrating experimental methods and approaches to falciparum malaria.

Authors:  P A Winstanley; W M Watkins
Journal:  Br J Clin Pharmacol       Date:  1992-06       Impact factor: 4.335

2.  Inhibitors of nonhousekeeping functions of the apicoplast defy delayed death in Plasmodium falciparum.

Authors:  T N C Ramya; Satyendra Mishra; Krishanpal Karmodiya; Namita Surolia; Avadhesha Surolia
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3.  Estimating sequestered parasite population dynamics in cerebral malaria.

Authors:  M B Gravenor; M B van Hensbroek; D Kwiatkowski
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-23       Impact factor: 11.205

4.  Potentiation of the antimalarial agent rufigallol.

Authors:  R W Winter; K A Cornell; L L Johnson; M Ignatushchenko; D J Hinrichs; M K Riscoe
Journal:  Antimicrob Agents Chemother       Date:  1996-06       Impact factor: 5.191

Review 5.  Progress and challenges in aminoacyl-tRNA synthetase-based therapeutics.

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6.  Altered temporal response of malaria parasites determines differential sensitivity to artemisinin.

Authors:  Nectarios Klonis; Stanley C Xie; James M McCaw; Maria P Crespo-Ortiz; Sophie G Zaloumis; Julie A Simpson; Leann Tilley
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-19       Impact factor: 11.205

7.  High-throughput analysis of antimalarial susceptibility data by the WorldWide Antimalarial Resistance Network (WWARN) in vitro analysis and reporting tool.

Authors:  Charles J Woodrow; Sabina Dahlström; Richard Cooksey; Jennifer A Flegg; Hervé Le Nagard; France Mentré; Claribel Murillo; Didier Ménard; François Nosten; Kanlaya Sriprawat; Lise Musset; Neils B Quashie; Pharath Lim; Rick M Fairhurst; Sam L Nsobya; Veronique Sinou; Harald Noedl; Bruno Pradines; Jacob D Johnson; Philippe J Guerin; Carol H Sibley; Jacques Le Bras
Journal:  Antimicrob Agents Chemother       Date:  2013-04-22       Impact factor: 5.191

Review 8.  Making the most of clinical data: reviewing the role of pharmacokinetic-pharmacodynamic models of anti-malarial drugs.

Authors:  Julie A Simpson; Sophie Zaloumis; Alysha M DeLivera; Ric N Price; James M McCaw
Journal:  AAPS J       Date:  2014-07-24       Impact factor: 4.009

9.  Defining the Effectiveness of Antimalarial Chemotherapy: Investigation of the Lag in Parasite Clearance Following Drug Administration.

Authors:  David S Khoury; Deborah Cromer; Jörg J Möhrle; James S McCarthy; Miles P Davenport
Journal:  J Infect Dis       Date:  2016-05-31       Impact factor: 5.226

Review 10.  Mefloquine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic efficacy.

Authors:  K J Palmer; S M Holliday; R N Brogden
Journal:  Drugs       Date:  1993-03       Impact factor: 9.546
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