BACKGROUND: Pancreatic cancer is one of the most challenging tumor entities worldwide, characterized as a highly aggressive disease with dismal overall prognosis and an incidence rate equaling mortality rate. OBJECTIVE: In order to have an update about pancreatic cancer incidence and evolution in North Africa, we conducted an epidemiological analytical retrospective study at the level of three Algerian regions: Sidi-bel-Abbes, Oran and Tlemcen along the last eight years [2006-2013]. METHODS: We performed a retrospective hospital-based study in which we analyzed the records of 160 pancreatic cancer patients registered, evaluated and treated in a Northern African region; at the level of hospital centers of the three western Algerian regions from 2006 to 2013. RESULTS: Along the period of study, 160 patients were diagnosed with pancreatic cancer; with a mean age of 66.2 years, and a sex ratio of 1.65; other parameters such as a medical history smoking and alcoholism history, tumor site; histological type as well as the stage of diagnosis were also enrolled in the study. Our statistical analyses reported a very significant correlation between patients who belonged to the age group of 21-40 years and the advanced stage of diagnosis (basing on TNM classification) with P=0.02. CONCLUSIONS: Pancreatic cancer is increasingly diagnosed in young adults at an advanced stage in North African regions.
BACKGROUND:Pancreatic cancer is one of the most challenging tumor entities worldwide, characterized as a highly aggressive disease with dismal overall prognosis and an incidence rate equaling mortality rate. OBJECTIVE: In order to have an update about pancreatic cancer incidence and evolution in North Africa, we conducted an epidemiological analytical retrospective study at the level of three Algerian regions: Sidi-bel-Abbes, Oran and Tlemcen along the last eight years [2006-2013]. METHODS: We performed a retrospective hospital-based study in which we analyzed the records of 160 pancreatic cancerpatients registered, evaluated and treated in a Northern African region; at the level of hospital centers of the three western Algerian regions from 2006 to 2013. RESULTS: Along the period of study, 160 patients were diagnosed with pancreatic cancer; with a mean age of 66.2 years, and a sex ratio of 1.65; other parameters such as a medical history smoking and alcoholism history, tumor site; histological type as well as the stage of diagnosis were also enrolled in the study. Our statistical analyses reported a very significant correlation between patients who belonged to the age group of 21-40 years and the advanced stage of diagnosis (basing on TNM classification) with P=0.02. CONCLUSIONS:Pancreatic cancer is increasingly diagnosed in young adults at an advanced stage in North African regions.
Entities:
Keywords:
North Africa; Pancreatic cancer; delayed diagnosis; young adults
Authors: Randall E Brand; Julia B Greer; Eugene Zolotarevsky; Rhonda Brand; Hongyan Du; Diane Simeone; Anna Zisman; Addi Gorchow; Shih-Yuan Connie Lee; Hemant K Roy; Michelle A Anderson Journal: Clin Gastroenterol Hepatol Date: 2009-06-26 Impact factor: 11.382
Authors: Ahmedin Jemal; Taylor Murray; Elizabeth Ward; Alicia Samuels; Ram C Tiwari; Asma Ghafoor; Eric J Feuer; Michael J Thun Journal: CA Cancer J Clin Date: 2005 Jan-Feb Impact factor: 508.702
Authors: Luigina Bonelli; Hugo Aste; Paolo Bovo; Giorgio Cavallini; Martina Felder; Riccardo Gusmaroli; Erminio Morandini; Paolo Ravelli; Romolo Briglia; Lucio Lombardo; Alberto De Micheli; Vittorio Pugliese Journal: Pancreas Date: 2003-08 Impact factor: 3.327