| Literature DB >> 26485407 |
Ali K Yetisen1, Haider Butt2, Lisa R Volpatti3, Ida Pavlichenko4, Matjaž Humar5, Sheldon J J Kwok6, Heebeom Koo7, Ki Su Kim7, Izabela Naydenova8, Ali Khademhosseini9, Sei Kwang Hahn10, Seok Hyun Yun11.
Abstract
Analyte-sensitive hydrogels that incorporate optical structures have emerged as sensing platforms for point-of-care diagnostics. The optical properties of the hydrogel sensors can be rationally designed and fabricated through self-assembly, microfabrication or laser writing. The advantages of photonic hydrogel sensors over conventional assay formats include label-free, quantitative, reusable, and continuous measurement capability that can be integrated with equipment-free text or image display. This Review explains the operation principles of photonic hydrogel sensors, presents syntheses of stimuli-responsive polymers, and provides an overview of qualitative and quantitative readout technologies. Applications in clinical samples are discussed, and potential future directions are identified.Entities:
Keywords: Block copolymers; Bragg stacks; Crystalline colloidal arrays; Holography; Hydrogels; In vitro diagnostics; Inverse opals; Layer-by-layer deposition; Photonic crystals; Plasmonics
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Year: 2015 PMID： 26485407 DOI： 10.1016/j.biotechadv.2015.10.005
Source DB: PubMed Journal: Biotechnol Adv ISSN： 0734-9750 Impact factor: 14.227