Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics.

Literature DB >> 26485365

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics.

Abstract

The spindle assembly checkpoint is a safeguard mechanism that coordinates cell-cycle progression during mitosis with the state of chromosome attachment to the mitotic spindle. The checkpoint prevents mitotic cells from exiting mitosis in the presence of unattached or improperly attached chromosomes, thus avoiding whole-chromosome gains or losses and their detrimental effects on cell physiology. Here, I review a considerable body of recent progress in the elucidation of the molecular mechanisms underlying checkpoint signaling, and identify a number of unresolved questions.

Entities: Disease

Mesh：

Year: 2015 PMID： 26485365 DOI： 10.1016/j.cub.2015.08.051

Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834

Keyword Cloud
Cited

290 in total

1. A biosensor-based approach reveals links between efflux pump expression and cell cycle regulation in pleiotropic drug resistance of yeast.

Authors: Jian Li; Kristen Kolberg; Ulrich Schlecht; Robert P St Onge; Ana Maria Aparicio; Joe Horecka; Ronald W Davis; Maureen E Hillenmeyer; Colin J B Harvey
Journal: J Biol Chem Date: 2018-12-04 Impact factor: 5.157

Review 2. Ubiquitin, the centrosome, and chromosome segregation.

Authors: Ying Zhang; Paul J Galardy
Journal: Chromosome Res Date: 2016-01 Impact factor: 5.239

3. Shrinking Daughters: Rlm1-Dependent G₁/S Checkpoint Maintains Saccharomyces cerevisiae Daughter Cell Size and Viability.

Authors: Sarah Piccirillo; Deepshikha Neog; David Spade; J David Van Horn; LeAnn M Tiede-Lewis; Sarah L Dallas; Tamas Kapros; Saul M Honigberg
Journal: Genetics Date: 2017-06-21 Impact factor: 4.562

4. A missense variant in NUF2, a component of the kinetochore NDC80 complex, causes impaired chromosome segregation and aneuploidy associated with microcephaly and short stature.

Authors: Daniela Tiaki Uehara; Hiroshi Mitsubuchi; Johji Inazawa
Journal: Hum Genet Date: 2021-03-15 Impact factor: 4.132

Review 5. Understanding eukaryotic chromosome segregation from a comparative biology perspective.

Authors: Snezhana Oliferenko
Journal: J Cell Sci Date: 2018-07-20 Impact factor: 5.285

Review 6. Spatiotemporal regulation of the Dma1-mediated mitotic checkpoint coordinates mitosis with cytokinesis.

Authors: Sierra N Cullati; Kathleen L Gould
Journal: Curr Genet Date: 2019-01-02 Impact factor: 3.886

7. C-terminal region of Mad2 plays an important role during mitotic spindle checkpoint in fission yeast Schizosaccharomyces pombe.

Authors: Gaurav Kumar Singh; Sharanbasappa Shrimant Karade; Rajeev Ranjan; Nafees Ahamad; Shakil Ahmed
Journal: Mol Biol Rep Date: 2016-09-23 Impact factor: 2.316

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics.

1. A biosensor-based approach reveals links between efflux pump expression and cell cycle regulation in pleiotropic drug resistance of yeast.

Review 2. Ubiquitin, the centrosome, and chromosome segregation.

3. Shrinking Daughters: Rlm1-Dependent G₁/S Checkpoint Maintains Saccharomyces cerevisiae Daughter Cell Size and Viability.

4. A missense variant in NUF2, a component of the kinetochore NDC80 complex, causes impaired chromosome segregation and aneuploidy associated with microcephaly and short stature.

Review 5. Understanding eukaryotic chromosome segregation from a comparative biology perspective.

Review 6. Spatiotemporal regulation of the Dma1-mediated mitotic checkpoint coordinates mitosis with cytokinesis.

7. C-terminal region of Mad2 plays an important role during mitotic spindle checkpoint in fission yeast Schizosaccharomyces pombe.

8. Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.

Review 9. Playing polo during mitosis: PLK1 takes the lead.

Review 10. Targeting the cell cycle in breast cancer: towards the next phase.

The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics.

1. A biosensor-based approach reveals links between efflux pump expression and cell cycle regulation in pleiotropic drug resistance of yeast.

Review 2. Ubiquitin, the centrosome, and chromosome segregation.

3. Shrinking Daughters: Rlm1-Dependent G1/S Checkpoint Maintains Saccharomyces cerevisiae Daughter Cell Size and Viability.

4. A missense variant in NUF2, a component of the kinetochore NDC80 complex, causes impaired chromosome segregation and aneuploidy associated with microcephaly and short stature.

Review 5. Understanding eukaryotic chromosome segregation from a comparative biology perspective.

Review 6. Spatiotemporal regulation of the Dma1-mediated mitotic checkpoint coordinates mitosis with cytokinesis.

7. C-terminal region of Mad2 plays an important role during mitotic spindle checkpoint in fission yeast Schizosaccharomyces pombe.

8. Mad2 Overexpression Uncovers a Critical Role for TRIP13 in Mitotic Exit.

Review 9. Playing polo during mitosis: PLK1 takes the lead.

Review 10. Targeting the cell cycle in breast cancer: towards the next phase.

3. Shrinking Daughters: Rlm1-Dependent G₁/S Checkpoint Maintains Saccharomyces cerevisiae Daughter Cell Size and Viability.