Literature DB >> 26485273

Correction: Modified Clonidine Testing for Growth Hormone Stimulation Reveals α2-Adrenoreceptor Sub Sensitivity in Children with Idiopathic Growth Hormone Deficiency.

Christian Willaschek, Sebastian Meint, Klaus Rager, Reiner Buchhorn.   

Abstract

Entities:  

Year:  2015        PMID: 26485273      PMCID: PMC4617883          DOI: 10.1371/journal.pone.0141291

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


× No keyword cloud information.
There are errors in Table 2. Please see the corrected Table 2 here.
Clonidine Test (Age matched T-Tests)
ParameterHealthy ControlConstitutional Growth DelayGrowth Hormone DeficiencySmall for Gestational Age
N 5636146
IgF1 [100–476 ng/ml] 86 ± 5676 ± 4243 ± 30
IgFPB3 [1900–5200 μg/l] 3075 ± 10762863 ± 12542538 ± 644
NT-pro-BNP [<289 ng/l] 162 ± 169178 ± 172177 ± 94
Heart Rate [bpm] 90 ± 1585 ± 11*** 85 ± 1183 ± 8*
SDNN [ms] 149 ± 51112 ± 27** 117 ± 33* 142 ± 40
RMSSD[ms] 46 ± 1851 ± 19* 50 ± 1777 ± 15**
RMSSD Day 34 ± 1541 ± 16** 37 ± 1653 ± 14**
RMSSD Night 61 ± 2665 ± 2470 ± 24108 ± 24**
Total Power 4957 ± 30293992 ± 20824000 ± 18737298 ± 2580**
Total Power Day 3889 ± 27473048 ± 16293286 ± 18634720 ± 1971*
Total Power Night 6287 ± 38435289 ± 31185111 ± 239110740 ± 3264**
VLF 2839 ± 22221960 ± 13272026 ± 10854831 ± 2678*
VLF Day 2256 ± 2016743 ± 1241666 ± 9472710 ± 1601
VLF Night 3534 ± 28442699 ± 24122581 ± 15957553 ± 3833*
LFn 60 ± 852 ± 10* 55 ± 1065 ± 12
LFn Day 65 ± 953 ± 9*** 59 ± 1161 ± 12
LFn Night 56 ± 10,651 ± 1453 ± 1270,8 ± 13
HF 731 ± 350817 ± 334759 ± 295747 ± 376
HF Day 456 ± 271636 ± 371** 553 ± 331633 ± 268*
HF Night 1100 ± 5561082 ± 4511079 ± 483945 ± 671
HF/LF 0.61 ± 0.220,85 ± 0,36* 0,78 ± 0,320,51 ± 0,33
HF/LF Day 0,45 ± 0,180,77 ± 0,34*** 0,65 ± 0,320,59 ± 0,40
HF/LF Night 0,79 ± 0,380,99 ± 0,550,95 ± 0,660,43 ± 0,30*

Laboratory data, data on 24- hour HRV, daytime und night time HRV from children with CGD, GHD and SGA compared to age-matched healthy controls.IgF1: Insuline like growth factor, IgFPB3: Insuline like growth factor binding proteine, NT-pro-BNP: N-terminal propeptide of brain natriuretic peptide, SDNN: Standard deviation of NN-intervalls, RMSSD: Root mean square standard deviation of adjacent NN Intervals, VLF: Very low frequency (< 0.04 Hz),LF: low frequency (LF, 0.04–0.15 Hz) HF: high frequency (HF, 0.15–0.4 Hz)

*** p < 0.001

** p < 0.01

* p < 0.5

Laboratory data, data on 24- hour HRV, daytime und night time HRV from children with CGD, GHD and SGA compared to age-matched healthy controls.IgF1: Insuline like growth factor, IgFPB3: Insuline like growth factor binding proteine, NT-pro-BNP: N-terminal propeptide of brain natriuretic peptide, SDNN: Standard deviation of NN-intervalls, RMSSD: Root mean square standard deviation of adjacent NN Intervals, VLF: Very low frequency (< 0.04 Hz),LF: low frequency (LF, 0.04–0.15 Hz) HF: high frequency (HF, 0.15–0.4 Hz) *** p < 0.001 ** p < 0.01 * p < 0.5
  1 in total

1.  Modified Clonidine Testing for Growth Hormone Stimulation Reveals α2-Adrenoreceptor Sub Sensitivity in Children with Idiopathic Growth Hormone Deficiency.

Authors:  Christian Willaschek; Sebastian Meint; Klaus Rager; Reiner Buchhorn
Journal:  PLoS One       Date:  2015-09-11       Impact factor: 3.240

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.