Literature DB >> 26484444

Pancreatic cancer: Classifying pancreatic cancer using gene expression profiling.

Michael Ayars1, Michael Goggins1.   

Abstract

Despite some advances in our understanding of the molecular characteristics of pancreatic cancer, much more progress is needed. In a new study, RNA profiling of pancreatic cancers was used to identify gene signatures of tumour cells and stromal cells to help predict patient outcomes.

Entities:  

Mesh：

Year:  2015        PMID： 26484444      PMCID： PMC5013537          DOI： 10.1038/nrgastro.2015.180

Source DB:  PubMed          Journal:  Nat Rev Gastroenterol Hepatol        ISSN： 1759-5045            Impact factor:   46.802


  9 in total

1.  Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation.

Authors:  Bella Kaufman; Ronnie Shapira-Frommer; Rita K Schmutzler; M William Audeh; Michael Friedlander; Judith Balmaña; Gillian Mitchell; Georgeta Fried; Salomon M Stemmer; Ayala Hubert; Ora Rosengarten; Mariana Steiner; Niklas Loman; Karin Bowen; Anitra Fielding; Susan M Domchek
Journal:  J Clin Oncol       Date:  2014-11-03       Impact factor: 44.544

2.  Advancing a clinically relevant perspective of the clonal nature of cancer.

Authors:  Christian Ruiz; Elizabeth Lenkiewicz; Lisa Evers; Tara Holley; Alex Robeson; Jeffrey Kiefer; Michael J Demeure; Michael A Hollingsworth; Michael Shen; Donna Prunkard; Peter S Rabinovitch; Tobias Zellweger; Spyro Mousses; Jeffrey M Trent; John D Carpten; Lukas Bubendorf; Daniel Von Hoff; Michael T Barrett
Journal:  Proc Natl Acad Sci U S A       Date:  2011-07-05       Impact factor: 11.205

3.  Projecting cancer incidence and deaths to 2030: the unexpected burden of thyroid, liver, and pancreas cancers in the United States.

Authors:  Lola Rahib; Benjamin D Smith; Rhonda Aizenberg; Allison B Rosenzweig; Julie M Fleshman; Lynn M Matrisian
Journal:  Cancer Res       Date:  2014-06-01       Impact factor: 12.701

Review 4.  Stromal reengineering to treat pancreas cancer.

Authors:  Ingunn M Stromnes; Kathleen E DelGiorno; Philip D Greenberg; Sunil R Hingorani
Journal:  Carcinogenesis       Date:  2014-06-07       Impact factor: 4.944

5.  PD-1 Blockade in Tumors with Mismatch-Repair Deficiency.

Authors:  Dung T Le; Jennifer N Uram; Hao Wang; Bjarne R Bartlett; Holly Kemberling; Aleksandra D Eyring; Andrew D Skora; Brandon S Luber; Nilofer S Azad; Dan Laheru; Barbara Biedrzycki; Ross C Donehower; Atif Zaheer; George A Fisher; Todd S Crocenzi; James J Lee; Steven M Duffy; Richard M Goldberg; Albert de la Chapelle; Minori Koshiji; Feriyl Bhaijee; Thomas Huebner; Ralph H Hruban; Laura D Wood; Nathan Cuka; Drew M Pardoll; Nickolas Papadopoulos; Kenneth W Kinzler; Shibin Zhou; Toby C Cornish; Janis M Taube; Robert A Anders; James R Eshleman; Bert Vogelstein; Luis A Diaz
Journal:  N Engl J Med       Date:  2015-05-30       Impact factor: 91.245

6.  Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma.

Authors:  Jeffrey R Infante; Hiroyuki Matsubayashi; Norihiro Sato; James Tonascia; Alison P Klein; Taylor A Riall; Charles Yeo; Christine Iacobuzio-Donahue; Michael Goggins
Journal:  J Clin Oncol       Date:  2007-01-20       Impact factor: 44.544

7.  DPC4 gene status of the primary carcinoma correlates with patterns of failure in patients with pancreatic cancer.

Authors:  Christine A Iacobuzio-Donahue; Baojin Fu; Shinichi Yachida; Mingde Luo; Hisashi Abe; Clark M Henderson; Felip Vilardell; Zheng Wang; Jesse W Keller; Priya Banerjee; Joseph M Herman; John L Cameron; Charles J Yeo; Marc K Halushka; James R Eshleman; Marian Raben; Alison P Klein; Ralph H Hruban; Manuel Hidalgo; Daniel Laheru
Journal:  J Clin Oncol       Date:  2009-03-09       Impact factor: 44.544

8.  The activated stroma index is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma.

Authors:  Mert Erkan; Christoph W Michalski; Simon Rieder; Carolin Reiser-Erkan; Ivane Abiatari; Armin Kolb; Nathalia A Giese; Irene Esposito; Helmut Friess; Jörg Kleeff
Journal:  Clin Gastroenterol Hepatol       Date:  2008-07-17       Impact factor: 11.382

9.  Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.

Authors:  Richard A Moffitt; Raoud Marayati; Elizabeth L Flate; Keith E Volmar; S Gabriela Herrera Loeza; Katherine A Hoadley; Naim U Rashid; Lindsay A Williams; Samuel C Eaton; Alexander H Chung; Jadwiga K Smyla; Judy M Anderson; Hong Jin Kim; David J Bentrem; Mark S Talamonti; Christine A Iacobuzio-Donahue; Michael A Hollingsworth; Jen Jen Yeh
Journal:  Nat Genet       Date:  2015-09-07       Impact factor: 38.330
  9 in total
  2 in total

Review 1.  Epigenetic Alterations and Mechanisms That Drive Resistance to Targeted Cancer Therapies.

Authors:  Narendra Wajapeyee; Romi Gupta
Journal:  Cancer Res       Date:  2021-09-16       Impact factor: 12.701

2.  The YAP1-NMU Axis Is Associated with Pancreatic Cancer Progression and Poor Outcome: Identification of a Novel Diagnostic Biomarker and Therapeutic Target.

Authors:  Wonbeak Yoo; Jaemin Lee; Eunsung Jun; Kyung Hee Noh; Sangmin Lee; Dana Jung; Kwang Hwa Jung; Ji-Su Kim; Yun-Yong Park; Song Cheol Kim; Seokho Kim
Journal:  Cancers (Basel)       Date:  2019-09-30       Impact factor: 6.639
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.