Literature DB >> 26483880

Paraneoplastic leukemoid reaction in pancreatic cancer: A case report.

Mélanie Dos Santos1, Karine Bouhier1, Manh-Thong Dao1.   

Abstract

Paraneoplastic leukemoid reaction is a rare syndrome defined by a leukocyte count exceeding 50 Giga/Liter (G/L), mostly described with progressive lung or renal carcinoma. We report a case of a 68-year-old man with recurrent pancreatic carcinoma presenting a leukemoid reaction with a white blood cell count of 63.87 G/L without identified infectious, iatrogenic or hematologic causes. His overall condition quickly degraded and he died three weeks after the discovery of the leukemoid reaction. This is the first case in French literature of leukemoid reaction in a patient with pancreatic carcinoma with poor prognostic value.

Entities:  

Keywords:  Leukemoid reaction; Pancreatic neoplasms; Paraneoplastic syndrome; Prognosis

Year:  2015        PMID: 26483880      PMCID: PMC4606180          DOI: 10.4251/wjgo.v7.i10.259

Source DB:  PubMed          Journal:  World J Gastrointest Oncol


  11 in total

1.  [Cancer of the pancreas and paraneoplastic leukemoid syndrome].

Authors:  B Godquin
Journal:  Chirurgie       Date:  1973-12-13

2.  [Paraneoplastic leukemoid reaction of a myeloid type or myeloid leukemia in cancer of the pancreas?].

Authors:  G Akoun; G Duhamel; P Duvaldestin; G Koubi; H Brocard
Journal:  Presse Med       Date:  1971-11-27       Impact factor: 1.228

3.  Granulocyte colony-stimulating factor and interleukin-6-producing lung cancer cell line, LCAM.

Authors:  M Inoue; M Minami; Y Fujii; H Matsuda; R Shirakura; T Kido
Journal:  J Surg Oncol       Date:  1997-04       Impact factor: 3.454

4.  Granulocytosis associated with tumor cell production of colony-stimulating activity.

Authors:  W Hocking; J Goodman; D Golde
Journal:  Blood       Date:  1983-03       Impact factor: 22.113

5.  Intense paraneoplastic neutrophilic leukemoid reaction related to a G-CSF-secreting lung sarcoma.

Authors:  Fabrice Jardin; Marc Vasse; Marc Debled; Stéphane Dominique; Philippe Courville; Françoise Callonnec; Gérard Buchonnet; Luc Thiberville; Hervé Tilly
Journal:  Am J Hematol       Date:  2005-11       Impact factor: 10.047

Review 6.  Leukemoid reaction in pancreatic cancer: a case report and review of the literature.

Authors:  Khusroo M Qureshi; Arun K Raman; Dongfeng Tan; Marwan G Fakih
Journal:  JOP       Date:  2006-11-10

7.  Leukemoid reaction resulting from multiple cytokine production in metastatic mucoepidermoid carcinoma with central necrosis.

Authors:  Y M Chen; J Whang-Peng; J M Liu; Y Chao; C R Lai; S Y Wang; R P Perng
Journal:  Jpn J Clin Oncol       Date:  1995-08       Impact factor: 3.019

8.  Extreme leucocytosis: not always leukaemia.

Authors:  C J M Halkes; H M Dijstelbloem; S J Eelkman Rooda; M H H Kramer
Journal:  Neth J Med       Date:  2007 Jul-Aug       Impact factor: 1.422

9.  Leukemoid reaction in a patient with adenocarcinoma of the lung: a case report.

Authors:  Hendrik Riesenberg; Frauke Müller; Martin Görner
Journal:  J Med Case Rep       Date:  2012-07-19

10.  Leukemoid reaction in sarcomatoid renal cell carcinoma: a two-case report.

Authors:  Weiping Huang; Feng Wang; Yeping Li; Feifei Duan; Zhixian Yu
Journal:  World J Surg Oncol       Date:  2014-04-19       Impact factor: 2.754

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  1 in total

Review 1.  Cerebral ischemic events in patients with pancreatic cancer: A retrospective cohort study of 17 patients and a literature review.

Authors:  Mathieu Bonnerot; Lisa Humbertjean; Gioia Mione; Jean-Christophe Lacour; Anne-Laure Derelle; Jean-Charles Sanchez; Nolwenn Riou-Comte; Sébastien Richard
Journal:  Medicine (Baltimore)       Date:  2016-06       Impact factor: 1.889

  1 in total

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