Literature DB >> 26483540

Proceedings: Using Stem Cell Therapies to Reestablish Osteogenic Capability for Bone Regeneration.

Neil Littman1, Arie Abo2.   

Abstract

UNLABELLED: The California Institute for Regenerative Medicine (CIRM) has invested approximately $70 million in programs targeting various orthopedic indications, including osteoporosis, bone fracture healing, vertebral compression fractures, and several others. The present article serves to outline the current state of CIRM's more advanced programs, comparing and contrasting them with the current standard of care and several other novel approaches under development. SIGNIFICANCE: This report describes CIRM bone programs that are in contrast to current cell therapy approaches. These projects aim to enhance stem cell activity for bone regeneration. ©AlphaMed Press.

Entities:  

Mesh：

Year:  2015        PMID： 26483540      PMCID： PMC4622413          DOI： 10.5966/sctm.2015-0202

Source DB:  PubMed          Journal:  Stem Cells Transl Med        ISSN： 2157-6564            Impact factor:   6.940


  4 in total

1.  Reengineering autologous bone grafts with the stem cell activator WNT3A.

Authors:  Wei Jing; Andrew A Smith; Bo Liu; Jingtao Li; Daniel J Hunter; Girija Dhamdhere; Benjamin Salmon; Jie Jiang; Du Cheng; Chelsey A Johnson; Serafine Chen; Katherine Lee; Gurpreet Singh; Jill A Helms
Journal:  Biomaterials       Date:  2015-02-02       Impact factor: 12.479

2.  Reversing bone loss by directing mesenchymal stem cells to bone.

Authors:  Wei Yao; Min Guan; Junjing Jia; Weiwei Dai; Yu-An E Lay; Sarah Amugongo; Ruiwu Liu; David Olivos; Mary Saunders; Kit S Lam; Jan Nolta; Diana Olvera; Robert O Ritchie; Nancy E Lane
Journal:  Stem Cells       Date:  2013-09       Impact factor: 6.277

3.  PTH promotes allograft integration in a calvarial bone defect.

Authors:  Dmitriy Sheyn; Doron Cohn Yakubovich; Ilan Kallai; Susan Su; Xiaoyu Da; Gadi Pelled; Wafa Tawackoli; Galen Cook-Weins; Edward M Schwarz; Dan Gazit; Zulma Gazit
Journal:  Mol Pharm       Date:  2013-11-08       Impact factor: 4.939

4.  Directing mesenchymal stem cells to bone to augment bone formation and increase bone mass.

Authors:  Min Guan; Wei Yao; Ruiwu Liu; Kit S Lam; Jan Nolta; Junjing Jia; Brian Panganiban; Liping Meng; Ping Zhou; Mohammad Shahnazari; Robert O Ritchie; Nancy E Lane
Journal:  Nat Med       Date:  2012-02-05       Impact factor: 53.440
  4 in total
  2 in total

Review 1.  Stem Cell-Derived Extracellular Vesicles as a Novel Potential Therapeutic Tool for Tissue Repair.

Authors:  Bi Chen; Qing Li; Bizeng Zhao; Yang Wang
Journal:  Stem Cells Transl Med       Date:  2017-06-27       Impact factor: 6.940

2.  Injection of synthetic mesenchymal stem cell mitigates osteoporosis in rats after ovariectomy.

Authors:  Miaoda Shen; Ronghuan Wu; Rilong Jin; Jun Pan; Fang Guo; Zhuoyang Li; Xiangjin Lin; Sanzhong Xu
Journal:  J Cell Mol Med       Date:  2018-05-16       Impact factor: 5.295
  2 in total

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