Literature DB >> 26482951

Gasdermin D: the long-awaited executioner of pyroptosis.

Si Ming Man1, Thirumala-Devi Kanneganti1.   

Abstract

Inflammatory caspases drive a lytic form of cell death called pyroptosis in response to microbial infection and endogenous damage-associated signals. Two studies now demonstrate that cleavage of the substrate gasdermin D by inflammatory caspases necessitates eventual pyroptotic demise of a cell.

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Year:  2015        PMID： 26482951      PMCID： PMC4650426          DOI： 10.1038/cr.2015.124

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  10 in total

1.  Non-canonical inflammasome activation targets caspase-11.

Authors:  Nobuhiko Kayagaki; Søren Warming; Mohamed Lamkanfi; Lieselotte Vande Walle; Salina Louie; Jennifer Dong; Kim Newton; Yan Qu; Jinfeng Liu; Sherry Heldens; Juan Zhang; Wyne P Lee; Merone Roose-Girma; Vishva M Dixit
Journal:  Nature       Date:  2011-10-16       Impact factor: 49.962

Review 2.  Regulation of inflammasome activation.

Authors:  Si Ming Man; Thirumala-Devi Kanneganti
Journal:  Immunol Rev       Date:  2015-05       Impact factor: 12.988

3.  Inflammatory stimuli regulate caspase substrate profiles.

Authors:  Nicholas J Agard; David Maltby; James A Wells
Journal:  Mol Cell Proteomics       Date:  2010-02-20       Impact factor: 5.911

4.  Targeted peptidecentric proteomics reveals caspase-7 as a substrate of the caspase-1 inflammasomes.

Authors:  Mohamed Lamkanfi; Thirumala-Devi Kanneganti; Petra Van Damme; Tom Vanden Berghe; Isabel Vanoverberghe; Joël Vandekerckhove; Peter Vandenabeele; Kris Gevaert; Gabriel Núñez
Journal:  Mol Cell Proteomics       Date:  2008-07-30       Impact factor: 5.911

5.  Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection.

Authors:  Gilad Doitsh; Nicole L K Galloway; Xin Geng; Zhiyuan Yang; Kathryn M Monroe; Orlando Zepeda; Peter W Hunt; Hiroyu Hatano; Stefanie Sowinski; Isa Muñoz-Arias; Warner C Greene
Journal:  Nature       Date:  2014-01-23       Impact factor: 49.962

6.  Inflammatory caspases are innate immune receptors for intracellular LPS.

Authors:  Jianjin Shi; Yue Zhao; Yupeng Wang; Wenqing Gao; Jingjin Ding; Peng Li; Liyan Hu; Feng Shao
Journal:  Nature       Date:  2014-08-06       Impact factor: 49.962

7.  Noncanonical inflammasome activation by intracellular LPS independent of TLR4.

Authors:  Nobuhiko Kayagaki; Michael T Wong; Irma B Stowe; Sree Ranjani Ramani; Lino C Gonzalez; Sachiko Akashi-Takamura; Kensuke Miyake; Juan Zhang; Wyne P Lee; Artur Muszyński; Lennart S Forsberg; Russell W Carlson; Vishva M Dixit
Journal:  Science       Date:  2013-07-25       Impact factor: 47.728

8.  Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE.

Authors:  S Wang; M Miura; Y K Jung; H Zhu; E Li; J Yuan
Journal:  Cell       Date:  1998-02-20       Impact factor: 41.582

9.  Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock.

Authors:  Jon A Hagar; Daniel A Powell; Youssef Aachoui; Robert K Ernst; Edward A Miao
Journal:  Science       Date:  2013-09-13       Impact factor: 47.728

10.  Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.

Authors:  Edward A Miao; Irina A Leaf; Piper M Treuting; Dat P Mao; Monica Dors; Anasuya Sarkar; Sarah E Warren; Mark D Wewers; Alan Aderem
Journal:  Nat Immunol       Date:  2010-11-07       Impact factor: 25.606
  10 in total
  41 in total

Review 1.  The role of glycine in regulated cell death.

Authors:  Joel M Weinberg; Anja Bienholz; M A Venkatachalam
Journal:  Cell Mol Life Sci       Date:  2016-04-11       Impact factor: 9.261

2.  Microparticulate Caspase 1 Regulates Gasdermin D and Pulmonary Vascular Endothelial Cell Injury.

Authors:  Srabani Mitra; Matthew Exline; Fabien Habyarimana; Mikhail A Gavrilin; Paul J Baker; Seth L Masters; Mark D Wewers; Anasuya Sarkar
Journal:  Am J Respir Cell Mol Biol       Date:  2018-07       Impact factor: 6.914

Review 3.  Neuronal Cell Death.

Authors:  Michael Fricker; Aviva M Tolkovsky; Vilmante Borutaite; Michael Coleman; Guy C Brown
Journal:  Physiol Rev       Date:  2018-04-01       Impact factor: 37.312

Review 4.  Gasdermin D (GSDMD) as a new target for the treatment of infection.

Authors:  Ankit Pandeya; Lan Li; Zhenyu Li; Yinan Wei
Journal:  Medchemcomm       Date:  2019-04-04       Impact factor: 3.597

5.  GSDMB promotes non-canonical pyroptosis by enhancing caspase-4 activity.

Authors:  Qin Chen; Peiliang Shi; Yufang Wang; Dayuan Zou; Xiuwen Wu; Dingyu Wang; Qiongyuan Hu; Yujie Zou; Zan Huang; Jianan Ren; Zhaoyu Lin; Xiang Gao
Journal:  J Mol Cell Biol       Date:  2019-06-01       Impact factor: 6.216

6.  Regulation and functions of NLRP3 inflammasome during influenza virus infection.

Authors:  Teneema Kuriakose; Thirumala-Devi Kanneganti
Journal:  Mol Immunol       Date:  2017-02-04       Impact factor: 4.407

Review 7.  The role of innate immunity in Alzheimer's disease.

Authors:  Hannah E Ennerfelt; John R Lukens
Journal:  Immunol Rev       Date:  2020-06-26       Impact factor: 12.988

Review 8.  Expanding Neutrophil Horizons: New Concepts in Inflammation.

Authors:  Simon M Chatfield; Nathalie Thieblemont; Véronique Witko-Sarsat
Journal:  J Innate Immun       Date:  2018-09-26       Impact factor: 7.349

Review 9.  COPs and POPs Patrol Inflammasome Activation.

Authors:  Mohanalaxmi Indramohan; Christian Stehlik; Andrea Dorfleutner
Journal:  J Mol Biol       Date:  2017-10-10       Impact factor: 5.469

10.  Characterisation of mice lacking the inflammatory caspases-1/11/12 reveals no contribution of caspase-12 to cell death and sepsis.

Authors:  Ranja Salvamoser; Kerstin Brinkmann; Lorraine A O'Reilly; Lachlan Whitehead; Andreas Strasser; Marco J Herold
Journal:  Cell Death Differ       Date:  2018-08-28       Impact factor: 15.828
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