Literature DB >> 2647703

L-671,329, a new antifungal agent. I. Fermentation and isolation.

R E Schwartz1, R A Giacobbe, J A Bland, R L Monaghan.   

Abstract

In screening for new antifungal agents from fungi, a new lipopeptide antifungal agent, L-671,329, similar to echinocandin B, has been isolated from Zalerion arboricola. Studies indicate that L-671,329 is produced under both solid and liquid fermentation conditions.

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Year:  1989        PMID： 2647703     DOI： 10.7164/antibiotics.42.163

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  11 in total

1.  Treatment of Pneumocystis carinii pneumonia with 1,3-beta-glucan synthesis inhibitors.

Authors:  D M Schmatz; M A Romancheck; L A Pittarelli; R E Schwartz; R A Fromtling; K H Nollstadt; F L Vanmiddlesworth; K E Wilson; M J Turner
Journal:  Proc Natl Acad Sci U S A       Date:  1990-08       Impact factor: 11.205

2.  A novel antiviral agent which inhibits the endonuclease of influenza viruses.

Authors:  J E Tomassini; M E Davies; J C Hastings; R Lingham; M Mojena; S L Raghoobar; S B Singh; J S Tkacz; M A Goetz
Journal:  Antimicrob Agents Chemother       Date:  1996-05       Impact factor: 5.191

3.  Effect of nystatin, amphotericin B and amphotericin B methyl ester on Saccharomyces cerevisiae with different lipid composition.

Authors:  M A de Resende; F Alterthum
Journal:  Mycopathologia       Date:  1990-12       Impact factor: 2.574

4.  Engineering of Glarea lozoyensis for exclusive production of the pneumocandin B0 precursor of the antifungal drug caspofungin acetate.

Authors:  Li Chen; Qun Yue; Yan Li; Xuemei Niu; Meichun Xiang; Wenzhao Wang; Gerald F Bills; Xingzhong Liu; Zhiqiang An
Journal:  Appl Environ Microbiol       Date:  2014-12-19       Impact factor: 4.792

5.  Efficient disruption of a polyketide synthase gene ( pks1) required for melanin synthesis through Agrobacterium-mediated transformation of Glarea lozoyensis.

Authors:  A Zhang; P Lu; A M Dahl-Roshak; P S Paress; S Kennedy; J S Tkacz; Z An
Journal:  Mol Genet Genomics       Date:  2003-01-10       Impact factor: 3.291

6.  Pharmacokinetics of L-671,329 in rhesus monkeys and DBA/2 mice.

Authors:  J G Sundelof; R Hajdu; W J Cleare; J Onishi; H Kropp
Journal:  Antimicrob Agents Chemother       Date:  1992-03       Impact factor: 5.191

7.  Heterologous transformation of Zalerion arboricola.

Authors:  R Kelly; E Register; M Sosa
Journal:  Curr Genet       Date:  1994-09       Impact factor: 3.886

8.  Improvement in the titer of echinocandin-type antibiotics: a magnesium-limited medium supporting the biphasic production of pneumocandins A0 and B0.

Authors:  J S Tkacz; R A Giacobbe; R L Monaghan
Journal:  J Ind Microbiol       Date:  1993-02

9.  In vitro antifungal activities and in vivo efficacies of 1,3-beta-D-glucan synthesis inhibitors L-671,329, L-646,991, tetrahydroechinocandin B, and L-687,781, a papulacandin.

Authors:  K Bartizal; G Abruzzo; C Trainor; D Krupa; K Nollstadt; D Schmatz; R Schwartz; M Hammond; J Balkovec; F Vanmiddlesworth
Journal:  Antimicrob Agents Chemother       Date:  1992-08       Impact factor: 5.191

Review 10.  Echinocandins: structural diversity, biosynthesis, and development of antimycotics.

Authors:  Wolfgang Hüttel
Journal:  Appl Microbiol Biotechnol       Date:  2020-12-03       Impact factor: 4.813
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