Literature DB >> 26476930

The biochemistry, enzymology and pharmacology of non-vitamin K anticoagulant drug reversal agents and antidotes.

Richard C Becker.   

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Year:  2016        PMID： 26476930     DOI： 10.1007/s11239-015-1286-3

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN： 0929-5305            Impact factor:   2.300


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  6 in total

1.  Idarucizumab for Dabigatran Reversal.

Authors:  Charles V Pollack; Paul A Reilly; John Eikelboom; Stephan Glund; Peter Verhamme; Richard A Bernstein; Robert Dubiel; Menno V Huisman; Elaine M Hylek; Pieter W Kamphuisen; Jörg Kreuzer; Jerrold H Levy; Frank W Sellke; Joachim Stangier; Thorsten Steiner; Bushi Wang; Chak-Wah Kam; Jeffrey I Weitz
Journal:  N Engl J Med       Date:  2015-06-22       Impact factor: 91.245

2.  A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa.

Authors:  Genmin Lu; Francis R DeGuzman; Stanley J Hollenbach; Mark J Karbarz; Keith Abe; Gail Lee; Peng Luan; Athiwat Hutchaleelaha; Mayuko Inagaki; Pamela B Conley; David R Phillips; Uma Sinha
Journal:  Nat Med       Date:  2013-03-03       Impact factor: 53.440

3.  A specific antidote for dabigatran: functional and structural characterization.

Authors:  Felix Schiele; Joanne van Ryn; Keith Canada; Corey Newsome; Eliud Sepulveda; John Park; Herbert Nar; Tobias Litzenburger
Journal:  Blood       Date:  2013-03-08       Impact factor: 22.113

4.  Nonclinical Safety Assessment of PER977: A Small Molecule Reversal Agent for New Oral Anticoagulants and Heparins.

Authors:  Dexter W Sullivan; Shayne C Gad; Bryan Laulicht; Sasha Bakhru; Solomon Steiner
Journal:  Int J Toxicol       Date:  2015-06-15       Impact factor: 2.032

5.  Use of PER977 to reverse the anticoagulant effect of edoxaban.

Authors:  Jack E Ansell; Sasha H Bakhru; Bryan E Laulicht; Solomon S Steiner; Michael Grosso; Karen Brown; Victor Dishy; Robert J Noveck; James C Costin
Journal:  N Engl J Med       Date:  2014-11-05       Impact factor: 91.245

Review 6.  Reversal agents in development for the new oral anticoagulants.

Authors:  James Costin; Jack Ansell; Bryan Laulicht; Sasha Bakhru; Solomon Steiner
Journal:  Postgrad Med       Date:  2014-11       Impact factor: 3.840
  6 in total
  1 in total

Review 1.  Direct-Acting Oral Anticoagulants and Their Reversal Agents-An Update.

Authors:  Stephanie A Kustos; Pius S Fasinu
Journal:  Medicines (Basel)       Date:  2019-10-15
  1 in total

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