Literature DB >> 26475727

Evolution of Hematopoietic Cell Transplantation for Immunoglobulin Light Chain Amyloidosis.

Taimur Sher1, Angela Dispenzieri2, Morie A Gertz2.   

Abstract

Immunoglobulin light chain amyloidosis is the most common type of systemic amyloidosis. Hematopoietic stem cell transplantation (HCT) is an effective treatment option for AL however due to multi-organ involvement in this disease HCT is feasible in a minority of patients. To maximize the benefit and minimize toxicity it is of paramount importance to optimize the selection of patients for HCT. In this review we discuss evolution of HCT and its typical application to a case of AL amyloidosis.
Copyright © 2016 American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  AL amyloidosis; Hematopoeitic stem cell transplantation; Immunoglobulin light chain amyloidosis; Stem cell transplantation

Mesh：

Substances：

Year:  2015        PMID： 26475727     DOI： 10.1016/j.bbmt.2015.10.010

Source DB:  PubMed          Journal:  Biol Blood Marrow Transplant        ISSN： 1083-8791            Impact factor:   5.742


  4 in total

Review 1.  Role of stem cell transplant and maintenance therapy in plasma cell disorders.

Authors:  Philip L McCarthy; Sarah A Holstein
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2016-12-02

Review 2.  Molecular Mechanism of Pathogenesis and Treatment Strategies for AL Amyloidosis.

Authors:  Hidehiko Ikura; Jin Endo; Hiroki Kitakata; Hidenori Moriyama; Motoaki Sano; Keiichi Fukuda
Journal:  Int J Mol Sci       Date:  2022-06-06       Impact factor: 6.208

3.  Effect of severe hypoalbuminemia on toxicity of high-dose melphalan and autologous stem cell transplantation in patients with AL amyloidosis.

Authors:  S Y Lee; R S Meehan; D C Seldin; J M Sloan; K Quillen; A Shelton; D Brauneis; V Sanchorawala
Journal:  Bone Marrow Transplant       Date:  2016-05-16       Impact factor: 5.483

4.  Significant role of magnetic resonance imaging for the diagnosis and evaluation of cardiac amyloidosis in primary light chain amyloidosis.

Authors:  Yasunobu Sekiguchi; Mutsumi Wakabayashi; Hiroko Iizuka; Haruko Takizawa; Keiji Sugimoto; Sakura Sakajiri; Tadaaki Inano; Yasutaka Fukuda; Yasuharu Hamano; Shigeki Tomita; Hiroshi Izumi; Hiroyuki Isogai; Mitsuo Okubo; Noriko Nakamura; Tomohiro Sawada; Kimihiro Matsumoto; Masaaki Noguchi
Journal:  J Clin Exp Hematop       Date:  2020-08-08
  4 in total

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