Literature DB >> 2647516

Immunological evidence that insulin activates protein kinase C in BC3H-1 myocytes.

M Acevedo-Duncan1, D R Cooper, M L Standaert, R V Farese.   

Abstract

Effects of insulin on immunoreactive protein kinase C were examined in BC3H-1 myocytes. Insulin provoked rapid dose-dependent decreases in cytosolic enzyme, and transient increases and subsequent decreases in membrane-associated enzyme. Phorbol esters provoked similar changes. Our findings suggest that insulin provokes the translocative activation of protein kinase C.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2647516     DOI： 10.1016/0014-5793(89)81186-x

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  4 in total

Review 1.  Specific protein kinase C isoforms as transducers and modulators of insulin signaling.

Authors:  Sanford R Sampson; Denise R Cooper
Journal:  Mol Genet Metab       Date:  2006-06-23       Impact factor: 4.797

2.  Gangliosides inhibit PDGF-induced signal transduction events in U-1242 MG human glioma cells.

Authors:  H E Saqr; J D Walters; Z Guan; B T Stokes; A J Yates
Journal:  Neurochem Res       Date:  1995-11       Impact factor: 3.996

3.  Insulin modulation of intracellular free magnesium in heart: involvement of protein kinase C.

Authors:  T Amano; T Matsubara; J Watanabe; S Nakayama; N Hotta
Journal:  Br J Pharmacol       Date:  2000-06       Impact factor: 8.739

4.  Effects of insulin and phorbol esters on MARCKS (myristoylated alanine-rich C-kinase substrate) phosphorylation (and other parameters of protein kinase C activation) in rat adipocytes, rat soleus muscle and BC3H-1 myocytes.

Authors:  T P Arnold; M L Standaert; H Hernandez; J Watson; H Mischak; M G Kazanietz; L Zhao; D R Cooper; R V Farese
Journal:  Biochem J       Date:  1993-10-01       Impact factor: 3.857
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.