| Literature DB >> 26474940 |
Jennifer A Whitty1, Julie Ratcliffe2, Elizabeth Kendall3, Paul Burton4, Andrew Wilson5, Peter Littlejohns6, Paul Harris7, Rachael Krinks3, Paul A Scuffham8.
Abstract
OBJECTIVES: To derive priority weights for access to bariatric surgery for obese adults, from the perspective of the public.Entities:
Keywords: HEALTH ECONOMICS; obesity
Mesh:
Year: 2015 PMID: 26474940 PMCID: PMC4611181 DOI: 10.1136/bmjopen-2015-008919
Source DB: PubMed Journal: BMJ Open ISSN: 2044-6055 Impact factor: 2.692
Attributes and levels
| Attribute | Level |
|---|---|
| Current level of obesity |
Obesity (BMI 30 to less than 40 kg/m2) Severe obesity (BMI 40 to less than 50 kg/m2) Very severe obesity (BMI greater than 50 kg/m2) |
| Obesity-related conditions |
Already has obesity-related conditions Is at risk of developing obesity-related conditions |
| Age of person needing surgery |
20 years 35 years 50 years |
| Family history |
At least one parent or sibling is obese, has had weight issues since childhood No family history of obesity |
| Chance of maintaining a substantial (at least half) reduction in excess weight |
30% 50% 70% |
| Has shown commitment by responding to prescribed lifestyle intervention (ie, physical activity and diet) |
Has maintained a healthy lifestyle plan for several months, resulting in some weight loss, however is still in need of surgery Has not maintained a healthy lifestyle plan and has had no weight loss |
| Time already spent on surgery waiting list |
6 months 1 year 2 years |
BMI, body mass index.
Figure 1Example choice set.
MNL model parameters
| Attribute | Level | Coefficient | p Value | Lower 95% CI | Upper 95% CI |
|---|---|---|---|---|---|
| Level of obesity | Obesity | −0.306 | Ref | ||
| Severe obesity | * 0.019 | 0.094 | −0.003 | 0.041 | |
| Very severe obesity | *** 0.288 | ≤0.001 | 0.266 | 0.309 | |
| Obesity-related conditions | At risk of comorbidity | −0.205 | Ref | ||
| Already has comorbidity | *** 0.205 | ≤0.001 | 0.191 | 0.219 | |
| Age of person | 20 years | −0.038 | Ref | ||
| 35 years | 0.021 | 0.519 | −0.042 | 0.084 | |
| 50 years | 0.017 | 0.341 | −0.018 | 0.053 | |
| Family history | No family history | −0.082 | Ref | ||
| Family history | *** 0.082 | ≤0.001 | 0.070 | 0.094 | |
| Chance of maintaining weight loss | per % | *** 0.015 | ≤0.001 | 0.014 | 0.016 |
| Commitment | Not maintained health lifestyle | −0.611 | Ref | ||
| Maintained healthy lifestyle | *** 0.611 | ≤0.001 | 0.589 | 0.632 | |
| Time on wait list | per month | *** 0.031 | ≤0.001 | 0.029 | 0.033 |
Ref: Referent level for the model specified with fixed parameter (given effects coding parameter for referent is equal to the negative sum of the parameters for the other levels for the attribute.63).
***, **, *: Significance at 1%, 5%, 10% level.
MNL, multinomial logit model.
Priority weights (based on marginal rates of substitution for MNL model)
| Attribute | Level* | Priority weight (ie, MRS chance in %)† |
|---|---|---|
| Level of obesity | Severe obesity | 21.24 (19.46 to 23.04) |
| Very severe obesity | 38.81 (36.41 to 41.23) | |
| Obesity-related conditions | Already has comorbidity | 26.80 (25.24 to 28.37) |
| Age of person | Age 35 years | 3.84 (−0.31 to 8.00) |
| Age 50 years | 3.62 (1.30 to 5.93) | |
| Family history | Family history | 10.66 (9.75 to 11.58) |
| Commitment | Maintained healthy lifestyle | 79.81 (75.79 to 83.88) |
| Chance maintain weight loss | Per % above 30% | 1.00 (fixed weight) |
| Time on wait list | Per month above 6 months | 2.03 (1.89 to 2.16) |
*Referent levels for marginal rates of substitution (MRS): obesity, at risk of comorbid conditions, 20 years old, no family history of obesity, has not maintained a healthy lifestyle, has spent a maximum of 6 months on the waiting list and has a 30% chance of maintaining a substantial (at least 50%) reduction in excess weight.
†Bracket indicates 95% CI, estimated using the delta method.64
MNL, multinomial logit model.
Respondent characteristics
| Characteristic | Number | Per cent (n=1994)* | Australia† | |
|---|---|---|---|---|
| Gender | Female | 1038 | 52.1 | 50.2% |
| Age | Mean (SD) | 46.6 (16.5) | ||
| ≥50 years | 849 | 42.60 | 41.5% (≥ 15-year) | |
| State | Qld | 1484 | 74.40 | |
| SA | 510 | 25.60 | ||
| Indigenous | Yes | 50 | 2.50 | 2.5% |
| Born in Australia‡ | Yes | 1472 | 73.80 | 72.3% |
| Main language spoken at home | English | 1875 | 94.00 | |
| Education (highest) | Certificate, Diploma or degree | 892 | 44.70 | 59% (25–64 year) |
| Employment | Part or full time | 1075 | 53.90 | 60.5% (≥15-year civilian population) |
| Worked in health system | Yes (during past 10 years) | 227 | 11.40 | |
| Income (annual household)‡ | >AU$100 000 | 374 | 21.80 | 35.1% (>AU$104 400) |
| Private health insurance | Hospital cover | 945 | 47.40 | 47% |
| Health | ||||
| AQoL-8D health state utility | Mean (SD) | 0.69 (0.21) | Mean 0.86 | |
| ≥0.8 | 750 | 37.84 | ||
| BMI | ≥25 | 1171 | 60.10 | 61.4% |
| Perceived weight‡ | Overweight or obese | 1052 | 53.50 | |
| Health service | ||||
| Hospital admissions | ≥1 in past 12 months | 399 | 20.01 | 13.2% |
| GP visits | ≥4 in past 12 months | 679 | 34.10 | 31.9% |
| Previous weight management surgery | For self or close family member | 141 | 7.10 | |
*Valid per cent for AQoL-8D health state utility (12 missing responses); Income (277 missing or prefer not to say); BMI (calculated from height and weight with 46 missing or prefer not to say); Perceived weight (29 missing or prefer not to say).
†Source for Australian demographic norms: Australian Bureau of Statistics (ABS) Catalogue 31010DO001_201403 Australian Demographic Statistics, Mar 2014 (gender, age); ABS Catalogue 2076.0 Census 2011 (Indigenous status); ABS Catalogue 3412.0 Migration, Australia, 2012–2013 (country of birth); ABS Catalogue 4102.0 Australian social trends 2007: Qualification of Australians (education); ABS Catalogue 6202.0 Labour Force Australia Oct 2014 (employment); ABS R Catalogue 6523.0 Household Income and Income Distribution, Australia, 2011–2012 (income); ABS Catalogue 4364.0 National Health Survey 2004–2005 (private health insurance); AQoL website http://www.aqol.com.au/index.php/norms (AQoL-8D); AIHW 20107 (BMI); ABS Catalogue 4839.0.55.001 Health Services: Patient Experiences in Australia, 2009 (hospital admissions and G.P. services).
‡Income, born in Australia and perceived weight were not entered into the LC model, since they displayed correlations above 0.3 with other included variables.
BMI, body mass index; GP, general practitioner.
Figure 2Priority weights for surgery according to criteria (from multinomial logit model model). Footnote to figure 2: Priority weights are relative to a score of zero for an individual who has obesity, is at risk of comorbid conditions rather than having developed them, has no family history, has not maintained a healthy lifestyle, has spent 6 months on the waiting list, and has a 30% chance of maintaining a substantial (at least 50%) reduction in excess weight. Priority points for time on wait list are per each month over 6 months and for change of maintaining weight loss are for each % over 30%.
Illustrative priority for three hypothetical patients, compared to a ‘referent case’
| ‘Referent case’ | Patient 1 | Patient 2 | Patient 3 | |
|---|---|---|---|---|
| Commitment | No | No | No | Yes |
| Level of obesity | Obese (BMI 30 to <40 kg/m2) | Severe (BMI ≥40 kg/m2) | Very severe (BMI ≥50 kg/m2) | Very severe (BMI ≥50 kg/m2) |
| Obesity-related conditions (comorbidity) | No | No | Yes | Yes |
| Family history | No | No | No | No |
| Time on wait list | ≤6 months | 12 months | 12 months | 6 months |
| Assumed chance maintain substantial reduction in weight loss | 30% | 30% | 40% | 50% |
BMI, body mass index.