Pseudomonas cepacia keratitis.

Pseudomonas cepacia has recently become recognized as a virulent pathogen responsible for nosocomial infections in hosts with altered immunity. It has been implicated in endophthalmitis and conjunctivitis, and is resistant to conventional antipseudomonal therapy. No cases of P. cepacia keratitis have been reported in the literature. We report such a case in association with topical steroid and contact lens use following penetrating keratoplasty. In addition, we developed an experimental model of P. cepacia keratitis in the rabbit. P. cepacia should be considered as a cause of infectious keratitis especially in nosocomial infections in immunocompromised corneas.