Literature DB >> 26474100

Contiguous triple spinal dysraphism associated with Chiari malformation Type II and hydrocephalus: an embryological conundrum between the unified theory of Pang and the unified theory of McLone.

Sivashanmugam Dhandapani1, Anirudh Srinivasan1.   

Abstract

Triple spinal dysraphism is extremely rare. There are published reports of multiple discrete neural tube defects with intervening normal segments that are explained by the multisite closure theory of primary neurulation, having an association with Chiari malformation Type II consistent with the unified theory of McLone. The authors report on a 1-year-old child with contiguous myelomeningocele and lipomyelomeningocele centered on Type I split cord malformation with Chiari malformation Type II and hydrocephalus. This composite anomaly is probably due to select abnormalities of the neurenteric canal during gastrulation, with a contiguous cascading impact on both dysjunction of the neural tube and closure of the neuropore, resulting in a small posterior fossa, probably bringing the unified theory of McLone closer to the unified theory of Pang.

Entities:  

Keywords:  CM-II = Chiari malformation Type II; Chiari malformation Type II; MMC = myelomeningocele; SCM = split cord malformation; congenital; contiguous triple spinal dysraphism; lipo-MMC = lipomyelomeningocele; lipomyelomeningocele; myelomeningocele; spine; split cord; unified theory of McLone; unified theory of Pang

Mesh:

Year:  2015        PMID: 26474100     DOI: 10.3171/2015.6.PEDS15179

Source DB:  PubMed          Journal:  J Neurosurg Pediatr        ISSN: 1933-0707            Impact factor:   2.375


  4 in total

1.  Lateral lipomyelomeningocele of the hemicord with split cord malformation type I revealed by 3D heavily T2-weighted MR imaging.

Authors:  Nobuya Murakami; Takato Morioka; Masako Ichiyama; Ryoko Nakamura; Nobuko Kawamura
Journal:  Childs Nerv Syst       Date:  2017-02-28       Impact factor: 1.475

Review 2.  Enhancing nodular lesions in Chiari II malformations in the setting of persistent hindbrain herniation: case report and literature review.

Authors:  Alexa Semonche; Ashish H Shah; Daniel G Eichberg; Sakir H Gultekin; Ricardo J Komotar; Michael E Ivan
Journal:  Childs Nerv Syst       Date:  2019-05-07       Impact factor: 1.475

3.  Tectal glioma presenting with clinical triad of obesity, amenorrhea and central cord syndrome with radiological pentad of hydrocephalus, empty sella, suprapineal diverticula, Chiari and syrinx.

Authors:  Sivashanmugam Dhandapani; Madhivanan Karthigeyan; Sushanta K Sahoo; Vivek Gupta
Journal:  Childs Nerv Syst       Date:  2016-10-18       Impact factor: 1.475

4.  Quality of Life Among Children Who Had Undergone Ventriculoperitoneal Shunt Surgery.

Authors:  Priyanka Prakash; Manju Dhandapani; Sandhya Ghai; Neena V Singh; Sivashanmugam Dhandapani
Journal:  J Pediatr Neurosci       Date:  2018 Apr-Jun
  4 in total

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