| Literature DB >> 26474100 |
Sivashanmugam Dhandapani1, Anirudh Srinivasan1.
Abstract
Triple spinal dysraphism is extremely rare. There are published reports of multiple discrete neural tube defects with intervening normal segments that are explained by the multisite closure theory of primary neurulation, having an association with Chiari malformation Type II consistent with the unified theory of McLone. The authors report on a 1-year-old child with contiguous myelomeningocele and lipomyelomeningocele centered on Type I split cord malformation with Chiari malformation Type II and hydrocephalus. This composite anomaly is probably due to select abnormalities of the neurenteric canal during gastrulation, with a contiguous cascading impact on both dysjunction of the neural tube and closure of the neuropore, resulting in a small posterior fossa, probably bringing the unified theory of McLone closer to the unified theory of Pang.Entities:
Keywords: CM-II = Chiari malformation Type II; Chiari malformation Type II; MMC = myelomeningocele; SCM = split cord malformation; congenital; contiguous triple spinal dysraphism; lipo-MMC = lipomyelomeningocele; lipomyelomeningocele; myelomeningocele; spine; split cord; unified theory of McLone; unified theory of Pang
Mesh:
Year: 2015 PMID: 26474100 DOI: 10.3171/2015.6.PEDS15179
Source DB: PubMed Journal: J Neurosurg Pediatr ISSN: 1933-0707 Impact factor: 2.375