Literature DB >> 26472736

Targeting leukemia's "fatty tooth".

Ismael Samudio1, Marina Konopleva2.   

Abstract

In this issue of Blood, Ricciardi et al report a novel fatty acid oxidation (FAO) inhibitor, ST1326, that effectively inhibits proliferation, survival, and chemoresistance in leukemia cell lines and primary samples.

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Year:  2015        PMID： 26472736     DOI： 10.1182/blood-2015-08-665125

Source DB:  PubMed          Journal:  Blood        ISSN： 0006-4971            Impact factor:   22.113


  11 in total

Review 1.  A "Weird" Mitochondrial Fatty Acid Oxidation as a Metabolic "Secret" of Cancer.

Authors:  Zhivko Zhelev; Ichio Aoki; Dessislava Lazarova; Tatyana Vlaykova; Tatsuya Higashi; Rumiana Bakalova
Journal:  Oxid Med Cell Longev       Date:  2022-02-08       Impact factor: 6.543

Review 2.  Fatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancer.

Authors:  Q Qu; F Zeng; X Liu; Q J Wang; F Deng
Journal:  Cell Death Dis       Date:  2016-05-19       Impact factor: 8.469

3.  High Expression of CPT1A Predicts Adverse Outcomes: A Potential Therapeutic Target for Acute Myeloid Leukemia.

Authors:  Jinlong Shi; Huaping Fu; Zhilong Jia; Kunlun He; Lin Fu; Weidong Wang
Journal:  EBioMedicine       Date:  2016-11-22       Impact factor: 8.143

4.  The plasma lipidome in acute myeloid leukemia at diagnosis in relation to clinical disease features.

Authors:  Thomas Pabst; Linda Kortz; Georg M Fiedler; Uta Ceglarek; Jeffrey R Idle; Diren Beyoğlu
Journal:  BBA Clin       Date:  2017-03-08

Review 5.  Targeting Metabolic Reprogramming in Acute Myeloid Leukemia.

Authors:  Isabel Castro; Belém Sampaio-Marques; Paula Ludovico
Journal:  Cells       Date:  2019-08-24       Impact factor: 6.600

Review 6.  Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia.

Authors:  Lucille Stuani; Marie Sabatier; Jean-Emmanuel Sarry
Journal:  BMC Biol       Date:  2019-07-18       Impact factor: 7.431

Review 7.  Redox Homeostasis and Metabolism in Cancer: A Complex Mechanism and Potential Targeted Therapeutics.

Authors:  Alia Ghoneum; Ammar Yasser Abdulfattah; Bailey Olivia Warren; Junjun Shu; Neveen Said
Journal:  Int J Mol Sci       Date:  2020-04-28       Impact factor: 5.923

8.  Novel Mango Ginger Bioactive (2,4,6-Trihydroxy-3,5-diprenyldihydrochalcone) Inhibits Mitochondrial Metabolism in Combination with Avocatin B.

Authors:  Varsha Jayasankar; Nikolina Vrdoljak; Alessia Roma; Nawaz Ahmed; Matthew Tcheng; Mark D Minden; Paul A Spagnuolo
Journal:  ACS Omega       Date:  2022-01-07

9.  Multiomic analysis identifies CPT1A as a potential therapeutic target in platinum-refractory, high-grade serous ovarian cancer.

Authors:  Dongqing Huang; Shrabanti Chowdhury; Hong Wang; Sara R Savage; Richard G Ivey; Jacob J Kennedy; Jeffrey R Whiteaker; Chenwei Lin; Xiaonan Hou; Ann L Oberg; Melissa C Larson; Najmeh Eskandari; Davide A Delisi; Saverio Gentile; Catherine J Huntoon; Uliana J Voytovich; Zahra J Shire; Qing Yu; Steven P Gygi; Andrew N Hoofnagle; Zachary T Herbert; Travis D Lorentzen; Anna Calinawan; Larry M Karnitz; S John Weroha; Scott H Kaufmann; Bing Zhang; Pei Wang; Michael J Birrer; Amanda G Paulovich
Journal:  Cell Rep Med       Date:  2021-12-21

Review 10.  Exploring the Metabolic Landscape of AML: From Haematopoietic Stem Cells to Myeloblasts and Leukaemic Stem Cells.

Authors:  Yashar Mesbahi; Toby N Trahair; Richard B Lock; Patrick Connerty
Journal:  Front Oncol       Date:  2022-02-10       Impact factor: 6.244
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