Literature DB >> 26472523

Current challenges of lung cancer care in an aging population.

Paola Claudia Sacco1, Francesca Casaluce2, Assunta Sgambato2, Antonio Rossi1, Paolo Maione1, Giovanni Palazzolo3, Alba Napolitano4, Cesare Gridelli1.   

Abstract

Lung cancer is the most common cancer in the elderly with a high mortality rate. Despite the high incidence, the elderly are under-represented in clinical trials and under-treated in clinical practice. These patients have a higher prevalence of comorbid disease, higher polypharmacy interactions, and an increased risk of mortality and toxicity with cancer treatments, compared to younger patients. Often data about their treatments come from retrospective analysis including patients who do not reflect the general elderly population. However, elderly patients can often receive cancer treatment similar to younger patients and an active treatment should not be denied based on older age.

Entities:  

Keywords:  elderly patients; lung cancer; non-small-cell lung cancer; small cell lung cancer; therapeutic approaches

Mesh:

Year:  2015        PMID: 26472523     DOI: 10.1586/14737140.2015.1096201

Source DB:  PubMed          Journal:  Expert Rev Anticancer Ther        ISSN: 1473-7140            Impact factor:   4.512


  5 in total

1.  Lung Cancer in the Oldest Old: A Nation-Wide Study in The Netherlands.

Authors:  Karlijn J G Schulkes; Carin A M Pouw; Elisabeth J M Driessen; Leontine J R van Elden; Frederiek van den Bos; Maryska L G Janssen-Heijnen; Jan-Willem J Lammers; Marije E Hamaker
Journal:  Lung       Date:  2017-06-19       Impact factor: 2.584

2.  The synergistic effect of resveratrol in combination with cisplatin on apoptosis via modulating autophagy in A549 cells.

Authors:  Song Hu; Xiaolin Li; Rongrong Xu; Lingyun Ye; Hui Kong; Xiaoning Zeng; Hong Wang; Weiping Xie
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2016-04-15       Impact factor: 3.848

3.  Real-World Experience of Nivolumab in Non-small Cell Lung Cancer in Korea.

Authors:  Sun Min Lim; Sang-We Kim; Byoung Chul Cho; Jin Hyung Kang; Myung-Ju Ahn; Dong-Wan Kim; Young-Chul Kim; Jin Soo Lee; Jong-Seok Lee; Sung Yong Lee; Keon Uk Park; Ho Jung An; Eun Kyung Cho; Tae Won Jang; Bong-Seog Kim; Joo-Hang Kim; Sung Sook Lee; Im-Ii Na; Seung Soo Yoo; Ki Hyeong Lee
Journal:  Cancer Res Treat       Date:  2020-05-15       Impact factor: 4.679

4.  Development of quality indicators for non-small cell lung cancer care: a first step toward assessing and improving quality of cancer care in China.

Authors:  Xinyu Wang; Shaofei Su; Shouyi Li; Han Bao; Meiqi Zhang; Dan Liu; Hao Jiang; Jiaying Wang; Meina Liu
Journal:  BMC Cancer       Date:  2017-08-31       Impact factor: 4.430

5.  HSP70 regulates cell proliferation and apoptosis in actinomycin-D-treated lung cancer cells.

Authors:  Kai Zhang; Ruonan Zhai; Teng Xue; Xiaoyan Xu; Yanan Ren; Mingze Ma; Fengxian Shi; Hang Wang; Na Wang; Fang Zhou
Journal:  Transl Cancer Res       Date:  2020-02       Impact factor: 1.241

  5 in total

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