| Literature DB >> 26471558 |
Tao Ma1, Na Hu2, Chenxi Ding3, Qiulong Zhang1, Wencong Li1, Yourui Suo2, Honglun Wang2, Bo Bai4, Chenxu Ding5.
Abstract
Anthocyanins are the main compounds in Nitraria tangutorun Bobr. The enrichment and purification of anthocyanins on macroporous resins were investigated. Regarding anthocyanin purification, static adsorption and desorption were studied. The optimal experimental conditions were the following: resin type: X-5; static adsorption time: 6h; desorption solution: ethanol-water-HCl (80:19:1, V/V/V; pH 1); desorption time: 40min. Furthermore, the in vitro and in vivo biological activities of the anthocyanins were evaluated. The anthocyanins showed ideal scavenging effects on free radicals in vitro, especially on 1,1-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl free radical (OH). In the animal experiment, blood lipid metabolism of hyperlipidemia rats was regulated by anthocyanin contents. The superoxide dismutase (SOD) activity and the total antioxidant capacity (TAC) of hyperlipidemia rats were also improved by anthocyanins. These results showed that anthocyanins from N. tangutorun Bobr. fruits had potential biological activities in vivo as well as in vitro.Entities:
Keywords: Anthocyanins; Antioxidant activities; Enrichment; In vitro and in vivo; Nitraria tangutorun Bobr.
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Year: 2015 PMID： 26471558 DOI： 10.1016/j.foodchem.2015.07.110
Source DB: PubMed Journal: Food Chem ISSN： 0308-8146 Impact factor: 7.514