Literature DB >> 26471263

Neurocognitive complaints and functional status among patients with chronic fatigue syndrome and fibromyalgia.

Karen B Schmaling1, Karran L Betterton2.   

Abstract

PURPOSE: The purpose of this study was to conduct a longitudinal examination of cognitive complaints and functional status in patients with chronic fatigue syndrome (CFS) alone and those who also had fibromyalgia (CFS/FM).
METHODS: A total of 93 patients from a tertiary care fatigue clinic were evaluated on four occasions, each 6 months apart. Each evaluation included a tender point assessment, and self-reported functional status and cognitive complaints.
RESULTS: Patients with CFS/FM reported significantly worse physical functioning, more bodily pain, and more cognitive difficulties (visuo-perceptual ability and verbal memory) than patients with CFS alone. Over time, bodily pain decreased only for participants with CFS alone. Verbal memory problems were associated with more bodily pain for both patient groups, whereas visuo-perceptual problems were associated with worse functional status for patients with CFS alone.
CONCLUSIONS: This study adds to the literature on functional status, longitudinal course, and cognitive difficulties among patients with CFS and those with CFS and FM. The results suggest that patients with CFS/FM are more disabled, have more cognitive complaints, and improve more slowly over time than patients with CFS alone. Specific cognitive difficulties are related to worse functional status, which supports the addition of cognitive difficulties to the FM case criteria.

Entities:  

Keywords:  Chronic fatigue syndrome; Fibromyalgia; Functional status; Neurocognitive symptoms

Mesh:

Year:  2015        PMID: 26471263      PMCID: PMC6115195          DOI: 10.1007/s11136-015-1160-y

Source DB:  PubMed          Journal:  Qual Life Res        ISSN: 0962-9343            Impact factor:   4.147


  27 in total

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3.  The chronic fatigue syndrome: a comprehensive approach to its definition and study. International Chronic Fatigue Syndrome Study Group.

Authors:  K Fukuda; S E Straus; I Hickie; M C Sharpe; J G Dobbins; A Komaroff
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4.  Comorbid clinical conditions in chronic fatigue: a co-twin control study.

Authors:  L A Aaron; R Herrell; S Ashton; M Belcourt; K Schmaling; J Goldberg; D Buchwald
Journal:  J Gen Intern Med       Date:  2001-01       Impact factor: 5.128

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6.  A European multicenter randomized double-blind placebo-controlled monotherapy clinical trial of milnacipran in treatment of fibromyalgia.

Authors:  Jaime C Branco; Olof Zachrisson; Serge Perrot; Yves Mainguy
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7.  Cognitive functioning in people with chronic fatigue syndrome: a comparison between subjective and objective measures.

Authors:  Susan J Cockshell; Jane L Mathias
Journal:  Neuropsychology       Date:  2013-12-23       Impact factor: 3.295

8.  Single-photon emission computerized tomography and neurocognitive function in patients with chronic fatigue syndrome.

Authors:  Karen B Schmaling; David H Lewis; Jessica I Fiedelak; Roderick Mahurin; Dedra S Buchwald
Journal:  Psychosom Med       Date:  2003 Jan-Feb       Impact factor: 4.312

9.  Cognitive functioning in chronic fatigue syndrome: a meta-analysis.

Authors:  S J Cockshell; J L Mathias
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10.  A comprehensive evaluation of standardized assessment tools in the diagnosis of fibromyalgia and in the assessment of fibromyalgia severity.

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Review 2.  Controversies and challenges in fibromyalgia: a review and a proposal.

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5.  A unifying theory for cognitive abnormalities in functional neurological disorders, fibromyalgia and chronic fatigue syndrome: systematic review.

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6.  Broad cognitive complaints but subtle objective working memory impairment in fibromyalgia patients.

Authors:  Marina Pidal-Miranda; Alberto Jacobo González-Villar; María Teresa Carrillo-de-la-Peña; Elena Andrade; Dolores Rodríguez-Salgado
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7.  Medically Unexplained Symptoms (MUS): Faults and Implications.

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  7 in total

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