| Literature DB >> 26470003 |
Raffaella Origa1, Alessandro Baldan2, Maria Marsella3, Caterina Borgna-Pignatti2.
Abstract
Patients with thalassemia major suffer from many complications, but in the last two decades their lives have improved both in length and quality. We report herein the most common complications and the recent advances that have changed the course of this disease. Also, we report in detail some of the new therapeutic strategies already introduced in practice and briefly some that are still being developed.Entities:
Keywords: HbF reactivation; JAK2; bisphosphonates; gene therapy; iron chelation; iron overload; magnetic resonance imaging; osteoporosis; sotatercept; stem cell transplantation
Mesh：
Year: 2015 PMID： 26470003 DOI： 10.1586/17474086.2015.1101339
Source DB: PubMed Journal: Expert Rev Hematol ISSN： 1747-4094 Impact factor: 2.929