M Praprotnik1, I Stucin Gantar2, M Lučovnik2, T Avčin3, U Krivec1. 1. Department of Pulmonology, University Children's Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia. 2. Division of Perinatology, Department of Gynecology and Obstretics, University Medical Centre Ljubljana, Ljubljana, Slovenia. 3. Department of Allergology, Rheumatology and Clinical Immunology, University Children's Hospital, University Medical Centre Ljubljana, Ljubljana, Slovenia.
Abstract
OBJECTIVE: To examine respiratory morbidity and exercise capacity at school age in children after bronchopulmonary dysplasia (BPD). STUDY DESIGN: Former preterm children after BPD (n=23), without BPD (n=33) and term controls (n=33) were compared using respiratory health questionnaire, spirometry and six-minute walk test (6MWT). RESULT: Wheezing was more frequent in BPD group (61%) vs non-BPD group (24%; P<0.001) and controls (15%; P<0.001) in the first year of life and until a year before inclusion. The children after BPD had lower mean value (P<0.001) for forced expiratory volume in 1 s (75.3%) vs non-BPD (89.8%) and controls (91.1%). Six-minute walking distance was lower after BPD by 58.3 m compared with non-BPD group (P=0.002) and by 53.7 m compared with controls (P=0.005). After adjusting for confounding factors the difference was not significant anymore. CONCLUSION: More frequent wheezing and reduced lung function persist into school age after BPD.
OBJECTIVE: To examine respiratory morbidity and exercise capacity at school age in children after bronchopulmonary dysplasia (BPD). STUDY DESIGN: Former preterm children after BPD (n=23), without BPD (n=33) and term controls (n=33) were compared using respiratory health questionnaire, spirometry and six-minute walk test (6MWT). RESULT: Wheezing was more frequent in BPD group (61%) vs non-BPD group (24%; P<0.001) and controls (15%; P<0.001) in the first year of life and until a year before inclusion. The children after BPD had lower mean value (P<0.001) for forced expiratory volume in 1 s (75.3%) vs non-BPD (89.8%) and controls (91.1%). Six-minute walking distance was lower after BPD by 58.3 m compared with non-BPD group (P=0.002) and by 53.7 m compared with controls (P=0.005). After adjusting for confounding factors the difference was not significant anymore. CONCLUSION: More frequent wheezing and reduced lung function persist into school age after BPD.
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