| Literature DB >> 26464083 |
J G Coen van Hasselt1, Piet H van der Graaf2.
Abstract
Quantitative systems pharmacology (QSP) modeling represents an emerging area of value to further streamline knowledge integration and to better inform decision making processes in drug development. QSP models reside at the interface between systems biology models and pharmacological models, yet their concrete implementation still needs to be established further. This review outlines key modeling techniques in both of these areas and to subsequently discuss challenges and opportunities for further integration, in oncology drug development.Mesh：
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Year: 2015 PMID： 26464083 DOI： 10.1016/j.ddtec.2015.06.004
Source DB: PubMed Journal: Drug Discov Today Technol ISSN： 1740-6749