BACKGROUND: To assess the role of early palliative care in patients with advanced oncologic and non-oncologic chronic diseases. METHODS: A qualitative systematic review of literature was performed. All the randomized phase III trials comparing early, simultaneous palliative care and standard care in patients with advanced oncologic and non-oncologic diseases were considered eligible and included into the analysis. The outcomes were classified into 6 classes: quality of life, symptoms control, overall survival, quality of care, patients' and caregivers' satisfaction, and costs of the assistance. RESULTS: Twelve papers reporting the data of 9 trials were considered eligible and included into the analysis. Two nonrandomized trials were also included into the selection because of the methods used by the authors. The early, simultaneous approach was reported to improve quality of life in two out of 7 papers, symptoms control in 1 out of 5 papers, overall survival in 2 out of 3 papers, quality of care in 5 out of 8 papers, patients' or caregivers' satisfaction in 3 out of 4 papers; and to reduce the costs of assistance in 2 out of 3 papers. CONCLUSION: Early palliative care improves the main outcomes of the assistance in patients with advanced oncologic and non-oncologic chronic diseases. The available data are probably enough to consider early palliative cares a novel standard of care in these groups of patients.
BACKGROUND: To assess the role of early palliative care in patients with advanced oncologic and non-oncologic chronic diseases. METHODS: A qualitative systematic review of literature was performed. All the randomized phase III trials comparing early, simultaneous palliative care and standard care in patients with advanced oncologic and non-oncologic diseases were considered eligible and included into the analysis. The outcomes were classified into 6 classes: quality of life, symptoms control, overall survival, quality of care, patients' and caregivers' satisfaction, and costs of the assistance. RESULTS: Twelve papers reporting the data of 9 trials were considered eligible and included into the analysis. Two nonrandomized trials were also included into the selection because of the methods used by the authors. The early, simultaneous approach was reported to improve quality of life in two out of 7 papers, symptoms control in 1 out of 5 papers, overall survival in 2 out of 3 papers, quality of care in 5 out of 8 papers, patients' or caregivers' satisfaction in 3 out of 4 papers; and to reduce the costs of assistance in 2 out of 3 papers. CONCLUSION: Early palliative care improves the main outcomes of the assistance in patients with advanced oncologic and non-oncologic chronic diseases. The available data are probably enough to consider early palliative cares a novel standard of care in these groups of patients.
Authors: Sharon M Watanabe; Viane Faily; Asifa Mawani; Ann Huot; Yoko Tarumi; Alexei Potapov; Konrad Fassbender; Alysa Fairchild; Anil A Joy; Karen M King; Wilson Roa; Christopher P Venner; Vickie E Baracos Journal: Oncologist Date: 2020-06-09
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Authors: Melisa Wilson; Rebekah H Anguiano; Rana L A Awdish; James C Coons; Amy Kimber; Melissa Morrison; Sara Paulus; Ann Schmit; Frank Spexarth; Keith M Swetz; Nathan J Verlinden; Mary E Whittenhall; Margaret R Sketch; Meredith Broderick; Jacqueline Brewer Journal: Pulm Circ Date: 2022-01-05 Impact factor: 2.886
Authors: Emanuela Scarpi; Monia Dall'Agata; Vittorina Zagonel; Teresa Gamucci; Raffaella Bertè; Elisabetta Sansoni; Elena Amaducci; Chiara Maria Broglia; Sara Alquati; Ferdinando Garetto; Stefania Schiavon; Silvia Quadrini; Elena Orlandi; Andrea Casadei Gardini; Silvia Ruscelli; Daris Ferrari; Maria Simona Pino; Roberto Bortolussi; Federica Negri; Silvia Stragliotto; Filomena Narducci; Martina Valgiusti; Alberto Farolfi; Oriana Nanni; Romina Rossi; Marco Maltoni Journal: Support Care Cancer Date: 2018-10-24 Impact factor: 3.603
Authors: F Amos Bailey; Beverly R Williams; Patricia S Goode; Richard E Kennedy; David T Redden; Elizabeth Kvale; Marie Bakitas; J Nicholas Dionne-Odom; Kathryn L Burgio Journal: J Gen Intern Med Date: 2021-02-05 Impact factor: 6.473
Authors: S Stacchiotti; A Gronchi; P Fossati; T Akiyama; C Alapetite; M Baumann; J Y Blay; S Bolle; S Boriani; P Bruzzi; R Capanna; A Caraceni; R Casadei; V Colia; J Debus; T Delaney; A Desai; P Dileo; S Dijkstra; F Doglietto; A Flanagan; S Froelich; P A Gardner; H Gelderblom; Z L Gokaslan; R Haas; C Heery; N Hindi; P Hohenberger; F Hornicek; R Imai; L Jeys; R L Jones; B Kasper; A Kawai; M Krengli; A Leithner; I Logowska; J Martin Broto; D Mazzatenta; C Morosi; P Nicolai; O J Norum; S Patel; N Penel; P Picci; S Pilotti; S Radaelli; F Ricchini; P Rutkowski; S Scheipl; C Sen; E Tamborini; K A Thornton; B Timmermann; V Torri; P U Tunn; M Uhl; Y Yamada; D C Weber; D Vanel; P P Varga; C L A Vleggeert-Lankamp; P G Casali; J Sommer Journal: Ann Oncol Date: 2017-06-01 Impact factor: 32.976
Authors: Barbara Kimbell; Scott A Murray; Heidi Byrne; Andrea Baird; Peter C Hayes; Alastair MacGilchrist; Anne Finucane; Patricia Brookes Young; Ronan E O'Carroll; Christopher J Weir; Marilyn Kendall; Kirsty Boyd Journal: Palliat Med Date: 2018-03-08 Impact factor: 4.762