| Literature DB >> 26463116 |
Michela Zuffo1, Filippo Doria1, Vincenzo Spalluto1, Sylvain Ladame2, Mauro Freccero3.
Abstract
A conceptually new light-up nucleic acid fluorescent probe resulting from the conjugation of a coumarin to a naphthalene diimide exhibits a single wavelength emission at 498 nm when free in solution and an additional red/NIR emission when bound to G-quadruplex DNA. The light-up response centred at 666 nm is highly specific for quadruplex DNA when compared to duplex DNA or to RNA quadruplexes.Entities:
Keywords: G-quadruplexes; dyes; fluorescent probes; naphthalene diimide; nucleic acids
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Year: 2015 PMID： 26463116 DOI： 10.1002/chem.201503020
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236