Nasim Hedayati1, Ann Brunson2, Chin-Shang Li3, Aaron C Baker4, William C Pevec4, Richard H White2, Patrick S Romano2. 1. Division of Vascular and Endovascular Surgery, University of California Davis Medical Center, CA, USA nhedayati@ucdavis.edu. 2. Department of Internal Medicine, University of California, Davis Medical Center, CA, USA. 3. Division of Biostatistics, Department of Public Health Sciences, University of California, Davis, Sacramento, CA, USA. 4. Division of Vascular and Endovascular Surgery, University of California Davis Medical Center, CA, USA.
Abstract
OBJECTIVES: Female gender has been shown to negatively affect the outcomes of surgical bypass for peripheral arterial disease (PAD). We examined gender-related disparities in outcomes of endovascular PAD procedures in a large population-based study. METHODS: We used discharge data from California hospitals to identify patients who had PAD interventions during 2005 to 2009. Logistic regression was used for 12-month reintervention, and Cox proportional hazard regression was used for amputation-free survival comparisons. RESULTS: A total of 25 635 patients had endovascular procedures (11 389 [44.4%] women). Women were more likely than men (34.5% vs 30.1%, P < .0001) to have critical limb ischemia (CLI). Twelve-month reintervention rate in women was similar to men. Amputation-free survival was better among women than men (hazard ratio 0.84, 95% confidence interval [CI] 0.76-0.93, P = .0006). CONCLUSION: Despite presenting more frequently with CLI, women had better amputation-free survival than men following endovascular procedures. Future research should determine whether findings favor one type of PAD treatment modality over another for women.
OBJECTIVES: Female gender has been shown to negatively affect the outcomes of surgical bypass for peripheral arterial disease (PAD). We examined gender-related disparities in outcomes of endovascular PAD procedures in a large population-based study. METHODS: We used discharge data from California hospitals to identify patients who had PAD interventions during 2005 to 2009. Logistic regression was used for 12-month reintervention, and Cox proportional hazard regression was used for amputation-free survival comparisons. RESULTS: A total of 25 635 patients had endovascular procedures (11 389 [44.4%] women). Women were more likely than men (34.5% vs 30.1%, P < .0001) to have critical limb ischemia (CLI). Twelve-month reintervention rate in women was similar to men. Amputation-free survival was better among women than men (hazard ratio 0.84, 95% confidence interval [CI] 0.76-0.93, P = .0006). CONCLUSION: Despite presenting more frequently with CLI, women had better amputation-free survival than men following endovascular procedures. Future research should determine whether findings favor one type of PAD treatment modality over another for women.
Authors: Maria Pabon; Susan Cheng; S Elissa Altin; Sanjum S Sethi; Michael D Nelson; Kerrie L Moreau; Naomi Hamburg; Connie N Hess Journal: Circ Res Date: 2022-02-17 Impact factor: 23.213
Authors: Ayman Elbadawi; Kirolos Barssoum; Michael Megaly; Devesh Rai; Ahmed Elsherbeeny; Hend Mansoor; Mehdi H Shishehbor; Ahmed Abdel-Latif; Martha Gulati; Islam Y Elgendy Journal: J Am Heart Assoc Date: 2021-09-17 Impact factor: 5.501