Literature DB >> 26462055

Synthesis of novel compounds containing morpholine and 5(4H)-oxazolone rings as potent tyrosinase inhibitors.

Hooshang Hamidian1, Sima Azizi2.   

Abstract

In this study, six new compounds containing morpholine and 5(4H)-oxazolone rings were synthesized. Structures of the new compounds using IR, (1)H NMR, mass spectroscopy and elemental analysis were characterized. All new compounds (4a-4f) have a strong inhibitory effect against mushroom tyrosinase. And the inhibitory effects of these compounds were compared with Kojic acid as standard.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  5(4H)-Oxazolone; Morpholine; Synthesis; Tyrosinase inhibitor

Mesh：

Substances：

Year:  2015        PMID： 26462055     DOI： 10.1016/j.bmc.2015.09.015

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  3 in total

1.  Synthesis, Spectroscopic Characterization and Polymerization Abilities of Blue and Green Light Emitting Oxazol-5-one Fluorophores.

Authors:  Gulsiye Ozturk Urut; Seher Aydin; Derya Topkaya; Elif Sahin; Serap Alp
Journal:  J Fluoresc       Date:  2018-05-21       Impact factor: 2.217

2.  Spectrofluorimetric and Potentiometric Determination of Acidity Constants of 4-(4'-Acetyloxy-3'-Methoxybenzylidene)-5-Oxazolone Derivatives.

Authors:  Derya Topkaya Taskiran; Gulsiye Ozturk Urut; Sevda Ayata; Serap Alp
Journal:  J Fluoresc       Date:  2016-11-19       Impact factor: 2.217

3.  Synthesis, Antimicrobial, Anti-Virulence and Anticancer Evaluation of New 5(4H)-Oxazolone-Based Sulfonamides.

Authors:  Ahmad J Almalki; Tarek S Ibrahim; Ehab S Taher; Mamdouh F A Mohamed; Mahmoud Youns; Wael A H Hegazy; Amany M M Al-Mahmoudy
Journal:  Molecules       Date:  2022-01-20       Impact factor: 4.411
  3 in total

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