Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules.

Literature DB >> 26460213

Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules.

Abstract

Breaking good: The amide bond is widely recognized as the strongest bond among the carboxylic acid derivatives. Therefore, the potential of amides to serve as synthetic building blocks has remained mostly untapped thus far. This Highlight describes a recent breakthrough that enables the catalytic conversion of amides into esters for the first time.

Entities: Chemical

Keywords: amides; esters; homogenous catalysis; nickel; solvolysis

Year: 2015 PMID： 26460213 DOI： 10.1002/anie.201508536

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

Keyword Cloud
Cited

13 in total

1. Chemoselective Transamidation of Thioamides by Transition-Metal-Free N-C(S) Transacylation.

Authors: Guangchen Li; Yangyang Xing; Hui Zhao; Jin Zhang; Xin Hong; Michal Szostak
Journal: Angew Chem Int Ed Engl Date: 2022-02-23 Impact factor: 15.336

Review 2. Acyclic Twisted Amides.

Authors: Guangrong Meng; Jin Zhang; Michal Szostak
Journal: Chem Rev Date: 2021-08-18 Impact factor: 72.087

Review 3. A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry.

Authors: Carlo Sambiagio; David Schönbauer; Remi Blieck; Toan Dao-Huy; Gerit Pototschnig; Patricia Schaaf; Thomas Wiesinger; Muhammad Farooq Zia; Joanna Wencel-Delord; Tatiana Besset; Bert U W Maes; Michael Schnürch
Journal: Chem Soc Rev Date: 2018-08-28 Impact factor: 54.564

Strong Bonds Made Weak: Towards the General Utility of Amides as Synthetic Modules.

1. Chemoselective Transamidation of Thioamides by Transition-Metal-Free N-C(S) Transacylation.

Review 2. Acyclic Twisted Amides.

Review 3. A comprehensive overview of directing groups applied in metal-catalysed C-H functionalisation chemistry.

4. Metal-Free C-H Alkyliminylation and Acylation of Alkenes with Secondary Amides.

5. Mild Reductive Functionalization of Amides into N-Sulfonylformamidines.

6. Tertiary amine synthesis via reductive coupling of amides with Grignard reagents.

7. Chemoselective Intermolecular Cross-Enolate-Type Coupling of Amides.

8. Iridium-catalyzed reductive Ugi-type reactions of tertiary amides.

9. Lewis Acid Enabled Copper-Catalyzed Asymmetric Synthesis of Chiral β-Substituted Amides.

10. Highly selective transition-metal-free transamidation of amides and amidation of esters at room temperature.