| Literature DB >> 26459475 |
N P Akent'eva1, S S Shushanov2, A I Kotel'nikov3.
Abstract
RHAMM-selective peptides in a concentration of 10 μg/ml (2×10(-7) M) inhibited the growth of MDA-MB-231 breast cancer cells over 48 h. Treatment of cancer cells with RHAMM-selective peptides induced apoptosis and necrosis and increased caspase-3 activity (by 30%).Entities:
Keywords: RHAMM-selective peptides; RHAMM/HMMR (hyaluronan-mediated motility receptor); apoptosis; breast cancer; necrosis
Mesh：
Substances：
Year: 2015 PMID： 26459475 DOI： 10.1007/s10517-015-3041-3
Source DB: PubMed Journal: Bull Exp Biol Med ISSN： 0007-4888 Impact factor: 0.804