Literature DB >> 26457680

Comprehensive review of the anatomy and physiology of male ejaculation: Premature ejaculation is not a disease.

Vincenzo Puppo1, Giulia Puppo2.   

Abstract

Human semen contains spermatozoa secreted by the testes and a mixture of components produced by the bulbo-urethral and Littre (paraurethral) glands, prostate, seminal vesicles, ampulla, and epididymis. Ejaculation is used as a synonym for the external ejection of semen, but it comprises two phases: emission and expulsion. As semen collects in the prostatic urethra, the rapid preorgasmic distension of the urethral bulb is pathognomonic of impeding orgasm, and the man experiences a sensation that ejaculation is inevitable (in women, emission is the only phase of orgasm). The semen is propelled along the penile urethra mainly by the bulbocavernosus muscle. With Kegel exercises, it is possible to train the perineal muscles. Immediately after the expulsion phase the male enters a refractory period, a recovery time during which further orgasm or ejaculation is physiologically impossible. Age affects the recovery time: as a man grows older, the refractory period increases. Sexual medicine experts consider premature ejaculation only in the case of vaginal intercourse, but vaginal orgasm has no scientific basis, so the duration of intercourse is not important for a woman's orgasm. The key to female orgasm are the female erectile organs; vaginal orgasm, G-spot, G-spot amplification, clitoral bulbs, clitoris-urethra-vaginal complex, internal clitoris and female ejaculation are terms without scientific basis. Female sexual dysfunctions are popular because they are based on something that does not exist, i.e. the vaginal orgasm. The physiology of ejaculation and orgasm is not impaired in premature ejaculation: it is not a disease, and non-coital sexual acts after male ejaculation can be used to produce orgasm in women. Teenagers and men can understand their sexual responses by masturbation and learn ejaculatory control with the stop-start method and the squeeze technique. Premature ejaculation must not be classified as a male sexual dysfunction. It has become the center of a multimillion dollar business: is premature ejaculation-and female sexual dysfunction-an illness constructed by sexual medicine experts under the influence of drug companies?
© 2015 Wiley Periodicals, Inc.

Entities:  

Keywords:  bulbocavernosus muscle; dapoxetine; ejaculation; orgasm; semen; sexual dysfunction

Mesh:

Year:  2015        PMID: 26457680     DOI: 10.1002/ca.22655

Source DB:  PubMed          Journal:  Clin Anat        ISSN: 0897-3806            Impact factor:   2.414


  10 in total

1.  Editorial Comment: Dorsolateral fibromuscular tissue preservation during artificial urinary sphincter cuff placement is associated with low infection and erosion rates.

Authors:  Luciano A Favorito
Journal:  Int Braz J Urol       Date:  2020 Jan-Feb       Impact factor: 1.541

Review 2.  Current and emerging treatment options for premature ejaculation.

Authors:  Murat Gul; Kadir Bocu; Ege Can Serefoglu
Journal:  Nat Rev Urol       Date:  2022-08-25       Impact factor: 16.430

3.  Loss of the Sympathetic Signal Produces Sterile Inflammation of the Prostate.

Authors:  Hao Hu; Yiwen Cui; Jing Yang; Ying Cao
Journal:  Front Mol Neurosci       Date:  2022-05-10       Impact factor: 6.261

4.  Perceptions, Expectations, Preferences, and Attitudes Toward Premature Ejaculation, Its Diagnosis and Topical Treatment with Fortacin™ Spray: Results from an Expert Panel Discussion.

Authors:  Ferdinando Fusco; Massimiliano Creta; Francesco Mangiapia; Lorenzo Cirigliano; Francesco Trama; Savio Domenico Pandolfo; Ciro Imbimbo; Nicola Longo; Vincenzo Mirone
Journal:  Res Rep Urol       Date:  2020-07-02

Review 5.  P2 purinergic receptor dysregulation in urologic disease.

Authors:  Janielle P Maynard; Karen S Sfanos
Journal:  Purinergic Signal       Date:  2022-06-10       Impact factor: 3.950

Review 6.  Neurons for Ejaculation and Factors Affecting Ejaculation.

Authors:  Kiran Kumar Soni; Han-Seong Jeong; Sujeong Jang
Journal:  Biology (Basel)       Date:  2022-04-29

Review 7.  Premature ejaculation: challenging new and the old concepts.

Authors:  Odunayo Kalejaiye; Khaled Almekaty; Gideon Blecher; Suks Minhas
Journal:  F1000Res       Date:  2017-12-04

Review 8.  Progresses in pharmaceutical and surgical management of premature ejaculation.

Authors:  Qin-Bo Hu; Dong Zhang; Liang Ma; Derry Mingyao Ng; Maria Haleem; Qi Ma
Journal:  Chin Med J (Engl)       Date:  2019-10-05       Impact factor: 2.628

9.  The Use of Delphi Method and Analytical Hierarchy Process in the Establishment of Assessment Tools in Premature Ejaculation: The Scoring System for Premature Ejaculation Treatment Outcomes.

Authors:  Jianzhong Zhang; Taoli Han; Zhonglin Cai; Ying Wang; Xuejun Shang; Bin Yang; Hongjun Li
Journal:  Am J Mens Health       Date:  2020 Nov-Dec

Review 10.  Role of Zinc (Zn) in Human Reproduction: A Journey from Initial Spermatogenesis to Childbirth.

Authors:  Sundaram Vickram; Karunakaran Rohini; Subramanian Srinivasan; David Nancy Veenakumari; Kumar Archana; Krishnan Anbarasu; Palanivelu Jeyanthi; Sundaram Thanigaivel; Govindarajan Gulothungan; Nanmaran Rajendiran; Padmalayam Sadanandan Srikumar
Journal:  Int J Mol Sci       Date:  2021-02-22       Impact factor: 5.923

  10 in total

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