| Literature DB >> 26456449 |
Bruce J Lanser1, Benjamin L Wright2, Kelly A Orgel3, Brian P Vickery3, David M Fleischer4.
Abstract
Food allergy is increasing in prevalence; as a result, there is intense focus on developing safe and effective therapies. Current methods of specific immunotherapy include oral, sublingual, and epicutaneous, while nonspecific methods that have been investigated include: Chinese herbal medicine, probiotics, and anti-IgE antibodies. Although some studies have demonstrated efficacy in inducing desensitization, questions regarding safety and the potential for achieving immune tolerance remain. Although some of these therapies demonstrate promise, further investigation is required before their incorporation into routine clinical practice.Entities:
Keywords: Anaphylaxis; Desensitization; Food allergy treatment; Food allergy/hypersensitivity; Immunotherapy; Omalizumab; Probiotics; Tolerance
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Year: 2015 PMID: 26456449 PMCID: PMC4970423 DOI: 10.1016/j.pcl.2015.07.015
Source DB: PubMed Journal: Pediatr Clin North Am ISSN: 0031-3955 Impact factor: 3.278