| Literature DB >> 26455435 |
T G Nelson1, C D Mitchell1, G M Sega-Hall1, R J Porter2.
Abstract
We describe a case of cutaneous diphtheria in the UK, presenting as lower leg ulcers in a returning traveller, and discuss the epidemiology, significance and public health implications of this disease and the therapeutic options available. A 65-year-old woman presented with a 6-week history of multiple ulcers appearing on her legs following a holiday in Kenya. Culture of biopsy tissue grew Corynebacterium diphtheriae. A cascade of therapeutic and public health interventions followed, many of which were terminated once the isolate was confirmed as nontoxigenic. Cutaneous diphtheria is a rare, notifiable disease in the UK, but is common in tropical countries, and is most often seen in the West as a traveller's disease. Corynebacteria are common skin commensals, and without appropriate clinical details, laboratories may not recognize C. diphtheriae/Corynebacterium ulcerans. This is likely to have led to under-reporting and under-recognition of the condition.Entities:
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Year: 2015 PMID: 26455435 DOI: 10.1111/ced.12763
Source DB: PubMed Journal: Clin Exp Dermatol ISSN: 0307-6938 Impact factor: 3.470