Saeed Ahmed Mahar1, Muhammad Shahid1, Aqiba Sarfaraz1, Zuhaib-u-Ddin Shaikh2, Shiraz Shaikh3, Nadia Shahid4. 1. Department of Endocrinology, Liaquat National Hospital and Medical College, Karachi. 2. Department of Medicine, Liaquat NationalHospital and Medical College, Karachi. 3. Department of Community Medicine, APPNA Institute of Public Health, Jinnah Sindh Medical University, Karachi. 4. Department of Medicine, Amjad Hospital, Karachi.
Abstract
OBJECTIVE: To assess the clinical presentations and short-term outcomes of patients with thyroiditis presenting to a tertiary care hospital in Karachi, Pakistan. STUDY DESIGN: Case series. PLACE AND DURATION OF STUDY: Department of Endocrinology, Liaquat National Hospital, Karachi, from June 2014 to February 2015. METHODOLOGY: Patients between 18 and 70 years of age with acute onset of thyroiditis confirmed on thyroid scan or clinical judgment presenting to the outpatient services were included in the study. Pregnant females, psychiatric patients and patients having other chronic illnesses were excluded from the study. RESULTS: A total of 26 patients with thyroiditis attended the endocrine clinic. Mean age of patients was 41.2 ± 11.12 years. There were 18 (69.2%) females. Clinical presentations were fever (65.4%), tender neck (23.1%), goiter (19.2%), localized tenderness in neck and palpable lymph nodes (26.9%). Major symptoms reported were: sore throat (69.2%), weight loss (38.5%), upper respiratory tract infection, thyroid pain, tremor, sweating and fever of unknown origin in 26.9% cases. All the patients had raised Erythrocyte Sedimentation Rate (ESR). Low Thyroid Stimulating Hormone (TSH) < 0.4 mlU/L was seen in 88.5% and 57.7% had raised Free T4 > 1.8 ng/dL. Complete recovery was seen in 88.5% patients while 11.5% had early hypothyroidism. CONCLUSION: Fever and sore throat were the main presenting features of thyroiditis patients. ESR was raised in all patients. A majority of patients had complete recovery with appropriate management; however, few cases developed hypothyroidism.
OBJECTIVE: To assess the clinical presentations and short-term outcomes of patients with thyroiditis presenting to a tertiary care hospital in Karachi, Pakistan. STUDY DESIGN: Case series. PLACE AND DURATION OF STUDY: Department of Endocrinology, Liaquat National Hospital, Karachi, from June 2014 to February 2015. METHODOLOGY:Patients between 18 and 70 years of age with acute onset of thyroiditis confirmed on thyroid scan or clinical judgment presenting to the outpatient services were included in the study. Pregnant females, psychiatricpatients and patients having other chronic illnesses were excluded from the study. RESULTS: A total of 26 patients with thyroiditis attended the endocrine clinic. Mean age of patients was 41.2 ± 11.12 years. There were 18 (69.2%) females. Clinical presentations were fever (65.4%), tender neck (23.1%), goiter (19.2%), localized tenderness in neck and palpable lymph nodes (26.9%). Major symptoms reported were: sore throat (69.2%), weight loss (38.5%), upper respiratory tract infection, thyroid pain, tremor, sweating and fever of unknown origin in 26.9% cases. All the patients had raised Erythrocyte Sedimentation Rate (ESR). Low Thyroid Stimulating Hormone (TSH) < 0.4 mlU/L was seen in 88.5% and 57.7% had raised Free T4 > 1.8 ng/dL. Complete recovery was seen in 88.5% patients while 11.5% had early hypothyroidism. CONCLUSION:Fever and sore throat were the main presenting features of thyroiditispatients. ESR was raised in all patients. A majority of patients had complete recovery with appropriate management; however, few cases developed hypothyroidism.