Literature DB >> 26454176

Localized dose delivering by ion beam irradiation for experimental trial of establishing brain necrosis model.

Takushi Takata1, Natsuko Kondo2, Yoshinori Sakurai2, Hiroki Tanaka2, Takashi Hasegawa3, Kyo Kume4, Minoru Suzuki2.   

Abstract

Localized dose delivery techniques to establish a brain radiation necrosis model are described. An irradiation field was designed by using accelerated protons or helium ions with a spread-out Bragg peak. Measurement of the designed field confirmed that a high dose can be confined to a local volume of an animal brain. The irradiation techniques described here are very useful for establishing a necrosis model without existence of extraneous complications.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Accelerated ion beam; Animal model; Brain radiation necrosis; Local volume irradiation; Spread-out Bragg peak

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Year:  2015        PMID： 26454176     DOI： 10.1016/j.apradiso.2015.07.023

Source DB:  PubMed          Journal:  Appl Radiat Isot        ISSN： 0969-8043            Impact factor:   1.513


  2 in total

1.  Persistent elevation of lysophosphatidylcholine promotes radiation brain necrosis with microglial recruitment by P2RX4 activation.

Authors:  Natsuko Kondo; Yoshinori Sakurai; Takushi Takata; Kuniyuki Kano; Kyo Kume; Munetoshi Maeda; Nobuhiko Takai; Shugo Suzuki; Fumihiro Eto; Kenji Kikushima; Hideki Wanibuchi; Shin-Ichi Miyatake; Takayuki Kajihara; Shoji Oda; Mitsutoshi Setou; Junken Aoki; Minoru Suzuki
Journal:  Sci Rep       Date:  2022-05-24       Impact factor: 4.996

2.  Extracellular Release of HMGB1 as an Early Potential Biomarker for the Therapeutic Response in a Xenograft Model of Boron Neutron Capture Therapy.

Authors:  Shoji Imamichi; Lichao Chen; Tasuku Ito; Ying Tong; Takae Onodera; Yuka Sasaki; Satoshi Nakamura; PierLuigi Mauri; Yu Sanada; Hiroshi Igaki; Yasufumi Murakami; Minoru Suzuki; Jun Itami; Shinichiro Masunaga; Mitsuko Masutani
Journal:  Biology (Basel)       Date:  2022-03-10
  2 in total

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