Literature DB >> 26451474

How Brain Fat Conquers Stress.

Michael A Welte1.   

Abstract

A new paper by Bailey et al. reveals that lipid droplets, crucial organelles for energy storage, can also protect against oxidative stress. In Drosophila larvae, lipid droplets in glia allow neuronal stem cells to keep proliferating under hypoxic conditions. Protection likely involves sequestering vulnerable membrane lipids away from reactive oxygen species.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 26451474     DOI： 10.1016/j.cell.2015.09.046

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  10 in total

Review 1.  Lipid droplet functions beyond energy storage.

Authors:  Michael A Welte; Alex P Gould
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2017-07-19       Impact factor: 4.698

2.  Functional Contribution of the Spastic Paraplegia-Related Triglyceride Hydrolase DDHD2 to the Formation and Content of Lipid Droplets.

Authors:  Jordon M Inloes; William B Kiosses; Huajin Wang; Tobias C Walther; Robert V Farese; Benjamin F Cravatt
Journal:  Biochemistry       Date:  2017-12-26       Impact factor: 3.162

Review 3.  Nutritional and Nanotechnological Modulators of Microglia.

Authors:  Dusica Maysinger; Issan Zhang
Journal:  Front Immunol       Date:  2016-07-15       Impact factor: 7.561

4.  Perilipin 5 Protects against Cellular Oxidative Stress by Enhancing Mitochondrial Function in HepG2 Cells.

Authors:  Yanjie Tan; Yi Jin; Qian Wang; Jin Huang; Xiang Wu; Zhuqing Ren
Journal:  Cells       Date:  2019-10-11       Impact factor: 6.600

Review 5.  Motility Plays an Important Role in the Lifetime of Mammalian Lipid Droplets.

Authors:  Yi Jin; Zhuqing Ren; Yanjie Tan; Pengxiang Zhao; Jian Wu
Journal:  Int J Mol Sci       Date:  2021-04-07       Impact factor: 5.923

6.  Lipid droplets contribute myogenic differentiation in C2C12 by promoting the remodeling of the acstin-filament.

Authors:  Yanjie Tan; Yi Jin; Pengxiang Zhao; Jian Wu; Zhuqing Ren
Journal:  Cell Death Dis       Date:  2021-11-23       Impact factor: 8.469

7.  Artificial Lipid Droplets: Novel Effective Biomaterials to Protect Cells against Oxidative Stress and Lipotoxicity.

Authors:  Pengxiang Zhao; Yi Jin; Xiang Wu; Jin Huang; Lupeng Chen; Yanjie Tan; Hong Yuan; Jian Wu; Zhuqing Ren
Journal:  Nanomaterials (Basel)       Date:  2022-02-17       Impact factor: 5.076

8.  ARP2/3 Regulates Fatty Acid Synthesis by Modulating Lipid Droplets' Motility.

Authors:  Pengxiang Zhao; Hongbo Han; Xiang Wu; Jian Wu; Zhuqing Ren
Journal:  Int J Mol Sci       Date:  2022-08-05       Impact factor: 6.208

9.  Transcriptional Regulation of Lipophorin Receptors Supports Neuronal Adaptation to Chronic Elevations of Activity.

Authors:  Jun Yin; Mary Gibbs; Caixia Long; Justin Rosenthal; Hyong S Kim; Anna Kim; Chengyu Sheng; Peng Ding; Uzma Javed; Quan Yuan
Journal:  Cell Rep       Date:  2018-10-30       Impact factor: 9.423

Review 10.  SEIPIN: A Key Factor for Nuclear Lipid Droplet Generation and Lipid Homeostasis.

Authors:  Yi Jin; Yanjie Tan; Pengxiang Zhao; Zhuqing Ren
Journal:  Int J Mol Sci       Date:  2020-11-02       Impact factor: 5.923
  10 in total

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