Literature DB >> 26451052

Tuberculosis trends over a five-year period at a tertiary care university-affiliated hospital in Singapore.

Suzanna Binte Jappar1, Su Ying Low1.   

Abstract

INTRODUCTION: Tuberculosis (TB), a potentially fatal infectious disease, poses significant health problems. The objective of this study was to analyse trends among newly diagnosed TB patients seen at the Singapore General Hospital (SGH).
METHODS: This study was a retrospective case record review of notified TB patients at SGH between 2006 and 2010 (inclusive).
RESULTS: A total of 1,979 cases of TB were notified over the five years. The number increased from 368 in 2006 to 407 in 2010 (p = 0.51), in tandem with the increasing number of patients seen at the hospital and the rising population in Singapore. Singaporean residents accounted for 82.8% of the cases, while non-Singaporean residents and non-residents made up the remainder. The year-to-year percentage of non-Singaporean residents and non-residents notified remained stable throughout the five years (p = 0.783). The number of male Singaporean residents (70.7%) notified was more than twice that of female Singaporean residents (29.3%). The majority of patients infected with TB (31.9%) were elderly patients aged > 65 years. Although testing for the human immunodeficiency virus increased from 43.8% (2006) to 64.2% (2010), the number detected with coinfection remained stable (14 and 12 patients in 2006 and 2010, respectively). Mortality rates also remained stable at 12.0%.
CONCLUSION: We cannot afford complacency, as there was no downward trend in the number of notified TB cases at SGH from 2006 to 2010. As the elderly contribute significantly to the TB burden, increased efforts are required to manage this vulnerable population.

Entities:  

Keywords:  HIV; elderly; trends; tuberculosis

Mesh:

Year:  2015        PMID: 26451052      PMCID: PMC4582129          DOI: 10.11622/smedj.2015134

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   1.858


  13 in total

1.  Does aging modify pulmonary tuberculosis?: A meta-analytical review.

Authors:  C Pérez-Guzmán; M H Vargas; A Torres-Cruz; H Villarreal-Velarde
Journal:  Chest       Date:  1999-10       Impact factor: 9.410

2.  Tuberculosis - an under-appreciated disease.

Authors:  Jeffery Cutter; Yee-Tang Wang
Journal:  Ann Acad Med Singapore       Date:  2010-03       Impact factor: 2.473

Review 3.  Immunosenescence: emerging challenges for an ageing population.

Authors:  Danielle Aw; Alberto B Silva; Donald B Palmer
Journal:  Immunology       Date:  2007-02-15       Impact factor: 7.397

4.  Tuberculosis in ageing: high rates, complex diagnosis and poor clinical outcomes.

Authors:  Luis Pablo Cruz-Hervert; Lourdes García-García; Leticia Ferreyra-Reyes; Miriam Bobadilla-del-Valle; Bulmaro Cano-Arellano; Sergio Canizales-Quintero; Elizabeth Ferreira-Guerrero; Renata Báez-Saldaña; Norma Téllez-Vázquez; Ariadna Nava-Mercado; Luis Juárez-Sandino; Guadalupe Delgado-Sánchez; César Alejandro Fuentes-Leyra; Rogelio Montero-Campos; Rosa Areli Martínez-Gamboa; Peter M Small; José Sifuentes-Osornio; Alfredo Ponce-de-León
Journal:  Age Ageing       Date:  2012-03-19       Impact factor: 10.668

Review 5.  Tuberculosis in the elderly.

Authors:  S Packham
Journal:  Gerontology       Date:  2001 Jul-Aug       Impact factor: 5.140

Review 6.  Tuberculosis in the elderly.

Authors:  S Rajagopalan; T T Yoshikawa
Journal:  Z Gerontol Geriatr       Date:  2000-10       Impact factor: 1.281

Review 7.  Tuberculosis and aging: a global health problem.

Authors:  S Rajagopalan
Journal:  Clin Infect Dis       Date:  2001-08-22       Impact factor: 9.079

8.  Human immunodeficiency virus testing in patients with newly-diagnosed tuberculosis in Singapore.

Authors:  S Y Low; P Eng
Journal:  Singapore Med J       Date:  2009-05       Impact factor: 1.858

9.  Tuberculosis in older people: a retrospective and comparative study from Hong Kong.

Authors:  Chi C Leung; Wing W Yew; Chi K Chan; Chi H Chau; Cheuk M Tam; Chak W Lam; Wai O Tam; Kam S Lau; Wai T Liu
Journal:  J Am Geriatr Soc       Date:  2002-07       Impact factor: 5.562

10.  Reported HIV status of tuberculosis patients--United States, 1993-2005.

Authors: 
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2007-10-26       Impact factor: 17.586

View more
  5 in total

1.  Modeling Survival Time to Death Among TB and HIV Co-infected Adult Patients: an Institution-Based Retrospective Cohort Study.

Authors:  Mesfin Esayas Lelisho; Belete Mulatu Teshale; Seid Ali Tareke; Sali Suleman Hassen; Solomon Abebaw Andargie; Amanuel Mengistu Merera; Sisay Awoke
Journal:  J Racial Ethn Health Disparities       Date:  2022-06-13

2.  Prevalence and Drug Resistance Pattern of Mycobacterium tuberculosis Isolated from Tuberculosis Patients in Basra, Iraq.

Authors:  Khairallah A S Mohammed; Ghorob S Khudhair; Dheyaa Bekheet Al-Rabeai
Journal:  Pol J Microbiol       Date:  2022-05-31

3.  A 5-year experience characterizing the demographic and clinical profile and directly observed treatment short-course treatment outcome in National Tuberculosis Center of Duhok province, Iraqi Kurdistan.

Authors:  Muayad Aghali Merza
Journal:  SAGE Open Med       Date:  2020-05-12

4.  Tuberculosis Status and Coinfection of Pulmonary Fungal Infections in Patients Referred to Reference Laboratory of Health Centers Ghaemshahr City during 2007-2017.

Authors:  Mohammad Reza Jabbari Amiri; Rora Siami; Azad Khaledi
Journal:  Ethiop J Health Sci       Date:  2018-11

5.  Factors associated with hospitalization and death among TB/HIV co-infected persons in Porto Alegre, Brazil.

Authors:  Maíra Rossetto; Évelin Maria Brand; Renata Mendonça Rodrigues; Laura Serrant; Luciana Barcellos Teixeira
Journal:  PLoS One       Date:  2019-01-02       Impact factor: 3.240

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.