| Literature DB >> 26449465 |
Jiyu Kim1,2, Sung-Woo Park1,2, Mu-Hyun Baik1,2, Sukbok Chang1,2.
Abstract
A complete switch in the Cp*Ir(III)-catalyzed paths between C-H olefination and hydroarylation was found to be crucially dependent on the type of directing groups. This dichotomy in product distribution was correlated to the efficiency in attaining syn-coplanarity of olefin-inserted 7-membered iridacycles. Theoretical studies support our hypothesis that the degree of flexibility of this key intermediate modulates the β-H elimination, which ultimately affords the observed chemoselectivity.Entities:
Year: 2015 PMID： 26449465 DOI： 10.1021/jacs.5b09824
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419