Alexandra Ceniceros1, Sonia Pértega2, Rita Galeiras3, Mónica Mourelo1, Eugenia López1, Javier Broullón4, Dolores Sousa5, David Freire1. 1. Burn Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain. 2. Clinical Epidemiology and Biostatistics Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain. 3. Burn Unit, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain. ritagaleiras@hotmail.es. 4. Department of Health Information Technology, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain. 5. Internal Medicine, Complexo Hospitalario Universitario A Coruña (CHUAC), SERGAS, As Xubias, 84, 15006, A Coruña, Spain.
Abstract
OBJECTIVE: To determine factors associated with mortality in burn patients with bacteraemia. BACKGROUND: Previous studies have shown the negative impact of bacteraemia on the prognosis of burn patients, but only a few of these have analysed variables intervening in the clinical progress of these patients. METHODS: A retrospective study of adult burn patients (n = 73) with bacteraemia (103 episodes) in a Burns Unit during the 2000-2013 period. The study collected demographic variables, and comorbidity, injury-related and clinical data related to bacteraemia. Variables related to hospital mortality were analysed using a multiple logistic regression model. RESULTS: The cumulative incidence of bacteraemia was 4.4 episodes/100 patients. The mean age was 53.3 ± 19.2 years (65.8 % male). The median total body surface area (TBSA) was 35 %, while 50.7 % of the population had inhalation syndrome. The mean SOFA score at the onset of bacteraemia was 2.7 ± 3.8. The most common pathogen was Pseudomonas aeruginosa (17.5 %). The mortality rate was 24.7 %. The variables that were significantly associated with mortality were age (OR = 1.13), TBSA (OR = 1.05), SOFA score at the onset of bacteraemia (OR = 1.53) and recurrent bacteraemia (OR = 41.6). CONCLUSION: In addition to conventional risk factors, recurrence and organ dysfunction at the onset of bacteraemia are also associated with mortality, while the pathogen involved is not a prognostic factor.
OBJECTIVE: To determine factors associated with mortality in burn patients with bacteraemia. BACKGROUND: Previous studies have shown the negative impact of bacteraemia on the prognosis of burn patients, but only a few of these have analysed variables intervening in the clinical progress of these patients. METHODS: A retrospective study of adult burn patients (n = 73) with bacteraemia (103 episodes) in a Burns Unit during the 2000-2013 period. The study collected demographic variables, and comorbidity, injury-related and clinical data related to bacteraemia. Variables related to hospital mortality were analysed using a multiple logistic regression model. RESULTS: The cumulative incidence of bacteraemia was 4.4 episodes/100 patients. The mean age was 53.3 ± 19.2 years (65.8 % male). The median total body surface area (TBSA) was 35 %, while 50.7 % of the population had inhalation syndrome. The mean SOFA score at the onset of bacteraemia was 2.7 ± 3.8. The most common pathogen was Pseudomonas aeruginosa (17.5 %). The mortality rate was 24.7 %. The variables that were significantly associated with mortality were age (OR = 1.13), TBSA (OR = 1.05), SOFA score at the onset of bacteraemia (OR = 1.53) and recurrent bacteraemia (OR = 41.6). CONCLUSION: In addition to conventional risk factors, recurrence and organ dysfunction at the onset of bacteraemia are also associated with mortality, while the pathogen involved is not a prognostic factor.
Authors: Bhavik M Patel; Jennifer D Paratz; Anthony Mallet; Jeffrey Lipman; Michael Rudd; Michael J Muller; David L Paterson; Jason A Roberts Journal: Burns Date: 2012-02-18 Impact factor: 2.744
Authors: Megan A Rech; Michael J Mosier; Kevin McConkey; Susan Zelisko; Giora Netzer; Elizabeth J Kovacs; Majid Afshar Journal: J Burn Care Res Date: 2019-04-26 Impact factor: 1.845