Literature DB >> 26449216

[Hyponatremia-induced life-threatening cerebral edema after ecstasy use].

S Baumann1, T Becher2, D Frambach2, H Wenz3, T Kirschning4, M Borggrefe2, S Rapp2, I Akin2.   

Abstract

Ecstasy, a psychoactive amphetamine derivative, is a popular party drug. We report the cases of 2 young adults who developed cerebral edema due to hyponatremia. One patient was released from the hospital without any sequelae, whereas the second patient died due to cerebral edema. Severe cases of symptomatic hyponatremia after ecstasy consumption are described in the literature with partially fatal clinical outcomes. Thus, physicians should be aware of early and consequent control of the sodium and choose an interdisciplinary treatment decision.

Entities:  

Keywords:  MDMA; Neurotransmitter; Pulmonary edema; Street drugs; Young adult

Mesh:

Substances:

Year:  2015        PMID: 26449216     DOI: 10.1007/s00063-015-0099-7

Source DB:  PubMed          Journal:  Med Klin Intensivmed Notfmed        ISSN: 2193-6218            Impact factor:   0.840


  11 in total

1.  Hyponatremia in marathon runners.

Authors:  Juan C Ayus; Alan Arieff; Michael L Moritz
Journal:  N Engl J Med       Date:  2005-07-28       Impact factor: 91.245

2.  MDMA-induced acute pulmonary edema in a patient without other organ dysfunction.

Authors:  Shih-Heng Chang; Ting-I Lai; Wen-Jone Chen; Cheng-Chung Fang
Journal:  Am J Emerg Med       Date:  2006-10       Impact factor: 2.469

3.  Near-fatal hyponatraemic coma due to vasopressin over-secretion after "ecstasy" (3,4-MDMA)

Authors:  R Holden; M A Jackson
Journal:  Lancet       Date:  1996-04-13       Impact factor: 79.321

4.  100 cc 3% sodium chloride bolus: a novel treatment for hyponatremic encephalopathy.

Authors:  Michael L Moritz; Juan Carlos Ayus
Journal:  Metab Brain Dis       Date:  2010-03-11       Impact factor: 3.584

5.  High incidence of mild hyponatraemia in females using ecstasy at a rave party.

Authors:  Geetruida D van Dijken; Renske E Blom; Ronald J Hené; Walther H Boer
Journal:  Nephrol Dial Transplant       Date:  2013-03-08       Impact factor: 5.992

Review 6.  The agony of ecstasy: MDMA (3,4-methylenedioxymethamphetamine) and the kidney.

Authors:  Garland A Campbell; Mitchell H Rosner
Journal:  Clin J Am Soc Nephrol       Date:  2008-08-06       Impact factor: 8.237

7.  Ecstasy-associated acute severe hyponatremia and cerebral edema: a role for osmotic diuresis?

Authors:  Abhijeet Ghatol; Amir Kazory
Journal:  J Emerg Med       Date:  2009-06-04       Impact factor: 1.484

Review 8.  Hyponatremia associated with 3,4-methylenedioxymethylamphetamine ("Ecstasy") abuse.

Authors:  Milos N Budisavljevic; Lisa Stewart; Steven A Sahn; David W Ploth
Journal:  Am J Med Sci       Date:  2003-08       Impact factor: 2.378

Review 9.  [Hyponatremia].

Authors:  S Heinrich; A Wagner; P Gross
Journal:  Med Klin Intensivmed Notfmed       Date:  2012-09-06       Impact factor: 0.840

10.  Moderate hyponatremia is associated with increased risk of mortality: evidence from a meta-analysis.

Authors:  Giovanni Corona; Corinna Giuliani; Gabriele Parenti; Dario Norello; Joseph G Verbalis; Gianni Forti; Mario Maggi; Alessandro Peri
Journal:  PLoS One       Date:  2013-12-18       Impact factor: 3.240

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