Literature DB >> 26447483

Establishment of an Ebola Treatment Unit and Laboratory - Bombali District, Sierra Leone, July 2014-January 2015.

Brigette Gleason, John Redd, Peter Kilmarx, Tom Sesay, Francis Bayor, Antons Mozalevskis, Allison Connolly, James Akpablie, Dimitri Prybylski, Daphne Moffett, Michael King, Micah Bass, Kristy Joseph, Jefferson Jones, Francis Ocen.   

Abstract

The first confirmed case of Ebola virus disease (Ebola) in Sierra Leone related to the ongoing epidemic in West Africa occurred in May 2014, and the outbreak quickly spread. To date, 8,704 Ebola cases and 3,955 Ebola deaths have been confirmed in Sierra Leone. The first Ebola treatment units (ETUs) in Sierra Leone were established in the eastern districts of Kenema and Kailahun, where the first Ebola cases were detected, and these districts were also the first to control the epidemic. By September and October 2014, districts in the western and northern provinces, including Bombali, had the highest case counts, but additional ETUs outside of the eastern province were not operational for weeks to months. Bombali became one of the most heavily affected districts in Sierra Leone, with 873 confirmed patients with Ebola during July-November 2014. The first ETU and laboratory in Bombali District were established in late November and early December 2014, respectively. T- evaluate the impact of the first ETU and laboratory becoming operational in Bombali on outbreak control, the Bombali Ebola surveillance team assessed epidemiologic indicators before and after the establishment of the first ETU and laboratory in Bombali. After the establishment of the ETU and laboratory, the interval from symptom onset to laboratory result and from specimen collection to laboratory result decreased. By providing treatment to Ebola patients and isolating contagious persons to halt ongoing community transmission, ETUs play a critical role in breaking chains of transmission and preventing uncontrolled spread of Ebola (4). Prioritizing and expediting the establishment of an ETU and laboratory by pre-positioning resources needed to provide capacity for isolation, testing, and treatment of Ebola are essential aspects of pre-outbreak planning.

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Year:  2015        PMID: 26447483     DOI: 10.15585/mmwr.mm6439a4

Source DB:  PubMed          Journal:  MMWR Morb Mortal Wkly Rep        ISSN: 0149-2195            Impact factor:   17.586


  8 in total

1.  Geospatial analysis of household spread of Ebola virus in a quarantined village - Sierra Leone, 2014.

Authors:  B L Gleason; S Foster; G E Wilt; B Miles; B Lewis; K Cauthen; M King; F Bayor; S Conteh; T Sesay; S I Kamara; G Lambert; P Finley; W Beyeler; T Moore; J Gaudioso; P H Kilmarx; J T Redd
Journal:  Epidemiol Infect       Date:  2017-08-22       Impact factor: 2.451

2.  Bolstering Community Cooperation in Ebola Resurgence Protocols: Combining Field Blood Draw and Point-of-Care Diagnosis.

Authors:  Mosoka P Fallah; Laura A Skrip; Philomena Raftery; Miata Kullie; Watta Borbor; A Scott Laney; David J Blackley; Athalia Christie; Emily Kainne Dokubo; Terrence Q Lo; Stewart Coulter; April Baller; Benjamin T Vonhm; Philip Bemah; Sowillie Lomax; Adolphus Yeiah; Yatta Wapoe-Sackie; Jennifer Mann; Peter Clement; Gloria Davies-Wayne; Esther Hamblion; Caitlin Wolfe; Desmond Williams; Alex Gasasira; Francis Kateh; Tolbert G Nyenswah; Alison P Galvani
Journal:  PLoS Med       Date:  2017-01-24       Impact factor: 11.069

3.  WASH activities at two Ebola treatment units in Sierra Leone.

Authors:  Michaela Mallow; Lee Gary; Timmy Jeng; Bob Bongomin; Miriam Tamar Aschkenasy; Peter Wallis; Hilarie H Cranmer; Estifanos Debasu; Adam C Levine
Journal:  PLoS One       Date:  2018-05-24       Impact factor: 3.240

4.  Phylodynamic Analysis of Ebola Virus Disease Transmission in Sierra Leone.

Authors:  Petrus Jansen van Vuren; Jason T Ladner; Antoinette A Grobbelaar; Michael R Wiley; Sean Lovett; Mushal Allam; Arshad Ismail; Chantel le Roux; Jacqueline Weyer; Naazneen Moolla; Nadia Storm; Joe Kgaladi; Mariano Sanchez-Lockhart; Ousman Conteh; Gustavo Palacios; Janusz T Paweska
Journal:  Viruses       Date:  2019-01-16       Impact factor: 5.048

5.  Reporting quality of the 2014 Ebola outbreak in Africa: A systematic analysis.

Authors:  Nina Huynh; Andrea Baumann; Mark Loeb
Journal:  PLoS One       Date:  2019-06-25       Impact factor: 3.240

6.  The practice of evaluating epidemic response in humanitarian and low-income settings: a systematic review.

Authors:  Abdihamid Warsame; Jillian Murray; Amy Gimma; Francesco Checchi
Journal:  BMC Med       Date:  2020-11-03       Impact factor: 8.775

7.  Estimation of Ebola's spillover infection exposure in Sierra Leone based on sociodemographic and economic factors.

Authors:  Sena Mursel; Nathaniel Alter; Lindsay Slavit; Anna Smith; Paolo Bocchini; Javier Buceta
Journal:  PLoS One       Date:  2022-09-01       Impact factor: 3.752

8.  Fears and Misperceptions of the Ebola Response System during the 2014-2015 Outbreak in Sierra Leone.

Authors:  Thespina Yamanis; Elisabeth Nolan; Susan Shepler
Journal:  PLoS Negl Trop Dis       Date:  2016-10-18
  8 in total

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